Could a zappy headband lift teen bipolar depression?

NCT ID NCT07246044

Recruiting now Symptom relief Sponsor: Jiangsu Province Nanjing Brain Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a gentle, non-invasive brain stimulation method called HD-tDCS in 100 teenagers with bipolar depression. Half get real stimulation, half get a fake version, and both continue their usual medications. Researchers will check if depression scores improve after two weeks and look at brain scans and other data to understand how it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-definition transcranial direct current stimulation (HD-tDCS)
What this could lead to: If it works, this could offer a non-drug option to ease depression symptoms in teenagers with bipolar disorder.
What could go wrong: This is an early-stage trial with no phase, so results are uncertain. The sham group may also improve, and benefits might be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bipolar depression bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADOLESCENT BIPOLAR DEPRESSION BIPOLAR DISORDER DEPRESSION PRIMARY SOMATOSENSORY CORTEX TDCS

Contacts and locations

Locations

Affiliated Nanjing Brain Hospital, Nanjing Medical University
RECRUITING

Nanjing, Jiangsu, 210000, China

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