ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Clinical trials for ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE explained in plain language.
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Promising new combo therapy for infant leukemia shows hope
Disease control Recruiting nowThis study tests whether adding two targeted drugs, blinatumomab and venetoclax, to standard chemotherapy can better treat infants with a type of leukemia called ALL. About 153 infants with newly diagnosed ALL will receive these combinations to see if they improve remission rates…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 03:43 UTC
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New strategy aims to stop transplant complications in kids with blood cancer
Disease control Recruiting nowThis study tests a new way to prevent chronic graft-versus-host disease (GVHD) in children and young adults with blood cancers who receive a donor stem cell transplant. Researchers remove a specific type of immune cell (naive T cells) from the donor cells before transplant to red…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 03:38 UTC
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New combo therapy aims to tackle tough blood cancers in kids
Disease control Recruiting nowThis early-phase study tests a drug called venetoclax combined with standard chemotherapy for children, teens, and young adults with aggressive blood cancers like leukemia and myelodysplastic syndrome. The goal is to find the safest dose and understand side effects. About 30 part…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: Andrew E. Place, MD • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Promising drug combo targets rare leukemia with poor prognosis
Disease control Recruiting nowThis study tests whether combining two drugs, venetoclax and azacitidine, can help people with a rare type of acute leukemia that is hard to treat. About 23 newly diagnosed patients aged 15 and older will receive the treatment to see if it improves remission rates. The goal is to…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Sheng-Li Xue, MD • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New hope for young leukemia patients: experimental drug combo enters safety trial
Disease control Recruiting nowThis early-stage study tests whether adding a new drug called revumenib to two standard chemotherapy drugs is safe for children and young adults whose acute myeloid leukemia (AML) has not responded to treatment or has returned. About 24 participants will receive the three-drug co…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New drug shows promise in preventing leukemia return after transplant
Disease control Recruiting nowThis early-phase study tests the safety and best dose of revumenib, a drug that blocks a protein fueling leukemia growth, in 27 adults and children with specific genetic types of acute leukemia. Participants take revumenib after a stem cell transplant to help keep the cancer from…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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New combo therapy aims to boost transplant success in older leukemia patients
Disease control Recruiting nowThis study tests a treatment plan for adults aged 60 and older with newly diagnosed, high-risk acute myeloid leukemia (AML) or similar blood cancers. The approach combines strong chemotherapy (FLAG-Ida) with a donor stem cell transplant given just days later, using lower-intensit…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New cord blood transplant approach targets tough blood cancers
Disease control Recruiting nowThis study tests a refined cord blood transplant method for people with high-risk blood cancers like leukemia and lymphoma. Participants receive chemotherapy and radiation before the transplant to prepare the body, then drugs after to prevent rejection. The goal is to improve sur…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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New hope for leukemia patients: targeted drug shows promise
Disease control Recruiting nowThis study tests a new drug called revumenib in people with certain types of leukemia that have come back or not responded to other treatments. The goal is to find the best dose and see if it can help control the disease. About 447 adults with specific genetic changes (MLL/KMT2A …
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1, PHASE2 • Sponsor: Syndax Pharmaceuticals • Aim: Disease control
Last updated May 04, 2026 16:31 UTC