ACUTE GRAFT VERSUS HOST DISEASE
Clinical trials for ACUTE GRAFT VERSUS HOST DISEASE explained in plain language.
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JAKAVI under the microscope: new study tracks GVHD treatment in real life
Disease control Recruiting nowThis study is tracking the safety and effectiveness of the drug JAKAVI (ruxolitinib) in 395 patients with graft-versus-host disease (GVHD), a complication of bone marrow transplants. Researchers are monitoring infections and other side effects in patients receiving the drug in ro…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Poop pills may tame deadly transplant complication
Disease control Recruiting nowThis study tests whether fecal microbiota transplantation (FMT) can safely treat gut graft-versus-host disease (GVHD), a serious complication after stem cell transplants. Researchers will track changes in stool frequency and volume in 50 participants aged 10 to 60. The goal is to…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Ancient heat therapy tested for Life-Threatening transplant complication
Disease control Recruiting nowThis study tests whether moxibustion, a traditional Chinese medicine technique that involves burning dried mugwort near the skin, can help people with a severe complication of stem cell transplants called graft-versus-host disease (GVHD) that does not respond to steroids. The tri…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE2 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New hope for transplant patients: drug combo may tame deadly immune attack
Disease control Recruiting nowThis study tests a drug called ruxolitinib for treating acute graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body after a bone marrow transplant. About 98 adults with moderate to severe GVHD will receive either ruxolitinib alone or wi…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE2 • Sponsor: John Levine • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New pill AC-003 tested for severe transplant complication
Disease control Recruiting nowThis early-phase trial is testing an experimental drug called AC-003 in 24 adults who have acute graft-versus-host disease (aGVHD) after a stem cell transplant and whose condition has not improved with steroids. The study aims to see if the drug is safe and tolerable, and to get …
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1 • Sponsor: Accro Bioscience (Suzhou) Limited • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Timing is everything: new trial aims to reduce transplant complications by adjusting when stem cells are given
Disease control Recruiting nowThis phase 3 trial is testing whether changing the timing of stem cell infusion after a single umbilical cord blood transplant can lower the risk of severe acute graft-versus-host disease (aGVHD) in people with blood cancers. The study will enroll 134 participants who are in remi…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New drug cocktail aims to tame transplant complication
Disease control Recruiting nowThis study tests a drug called gecacitinib (jaktinib) combined with steroids as a first treatment for acute graft-versus-host disease (GVHD), a serious complication after stem cell transplants. About 35 adults who have had a stem cell transplant and develop moderate to severe GVH…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Dental cleaning may ward off deadly transplant complication
Prevention Recruiting nowThis study tests whether a dental cleaning shortly after a stem cell transplant can prevent chronic graft-versus-host disease (GVHD), a common and serious complication. Researchers will enroll 45 adults receiving a donor stem cell transplant for blood cancer. The goal is to see i…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Exercise may tame steroid side effects in stem cell transplant patients
Symptom relief Recruiting nowThis study looks at whether a home-based aerobic and resistance exercise program is feasible for adults with graft-versus-host disease (GVHD) after a stem cell transplant. Participants will either do aerobic and resistance exercises or simple stretching. The goal is to see if exe…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC