ACUTE GRAFT VERSUS HOST DISEASE
Clinical trials for ACUTE GRAFT VERSUS HOST DISEASE explained in plain language.
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New combo aims to tame GVHD after stem cell transplants
Disease control OngoingThis early study tests whether combining a low-dose steroid with the drug ruxolitinib can better control grade II acute graft-versus-host disease (GVHD) after a stem cell transplant. GVHD occurs when donor immune cells attack the recipient's body. The trial includes 30 people wit…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1 • Sponsor: Daihong Liu • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Stem cell study to prevent transplant complications pulled before start
Disease control TerminatedThis study aimed to see if a special type of stem cell (hAESC) could safely prevent acute graft-versus-host disease in people receiving a stem cell transplant for blood cancer. It was designed for adults at high risk of this complication. However, the study was withdrawn before a…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Fish oil infusions tested to tame transplant complication
Disease control ENROLLING_BY_INVITATIONThis study tests whether daily intravenous omega-3 fatty acids (fish oil) can reduce the risk and severity of acute graft-versus-host disease (aGVHD) in 30 adults receiving a stem cell transplant. Participants get omega-3 infusions from before transplant until about 35 days after…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Fujian Medical University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Poop pills may shield stem cell patients from deadly immune attack
Prevention OngoingThis study tests whether giving patients a transplant of healthy gut bacteria (from donated stool) can prevent severe graft-versus-host disease (GVHD) after a stem cell transplant. GVHD is a serious complication where donor immune cells attack the patient's body. The trial involv…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 08:10 UTC
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Probiotic shows promise in preventing Life-Threatening transplant complication in kids
Prevention OngoingThis study tests whether a probiotic called Lactobacillus plantarum can prevent a serious complication called graft-versus-host disease (GvHD) in the gut of children receiving a donor stem cell transplant. About 173 children with blood cancers or other conditions are taking the p…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention
Last updated Jun 27, 2026 07:54 UTC
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Scientists investigate skin immune cells to understand Graft-Versus-Host disease
Knowledge-focused OngoingThis study looks at how different types of immune cells in the skin, called dendritic cells, are involved in graft-versus-host disease (GVHD) after a bone marrow transplant. Researchers will take small skin samples and blood from 22 adults with acute or chronic skin GVHD. The goa…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Timing is everything: new study tests if stem cell infusion time prevents transplant complications
Knowledge-focused OngoingThis study looks at whether the time when stem cells are given to blood cancer patients after a donor transplant affects their risk of developing acute graft-versus-host disease (aGVHD), a serious complication where donor cells attack the patient's body. About 198 patients aged 1…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC