ACUTE GRAFT VERSUS HOST DISEASE
Clinical trials for ACUTE GRAFT VERSUS HOST DISEASE explained in plain language.
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Experimental combo for Graft-Versus-Host disease fails to enroll
Disease control TerminatedThis study tested a mix of drugs (cyclophosphamide, sirolimus, low-dose IL-2, and azacitidine) to treat severe graft-versus-host disease that didn't respond to steroids. Only 3 patients were enrolled before the trial was stopped early. The goal was to see if the treatment could c…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New combo aims to tame deadly transplant complication with fewer steroids
Disease control TerminatedThis study tested a combination of three drugs (ruxolitinib, uhCG/EGF, and steroids) in 10 people with a severe form of acute graft-versus-host disease (aGVHD), a complication that can occur after a stem cell transplant. The goal was to find the lowest effective steroid dose to r…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Pediatric GVHD drug combo trial halted early after just 2 kids enrolled
Disease control TerminatedThis study tested a drug called itacitinib combined with steroids to treat acute graft-versus-host disease (aGVHD) in children. aGVHD is a serious complication where donor immune cells attack the child's body after a stem cell transplant. The trial was stopped early after enrolli…
Matched conditions: ACUTE GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC