ACUTE GRAFT-VERSUS-HOST DISEASE
Clinical trials for ACUTE GRAFT-VERSUS-HOST DISEASE explained in plain language.
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New hope for stem cell transplant complication: AC-003 trial launches
Disease control Recruiting nowThis early-stage trial tests a new drug called AC-003 in 24 adults who developed acute graft-versus-host disease (aGVHD) after a stem cell transplant and did not respond to standard steroids. The main goal is to check the drug's safety and how the body processes it, while also lo…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1 • Sponsor: Accro Bioscience (Suzhou) Limited • Aim: Disease control
Last updated May 17, 2026 04:16 UTC
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New drug combo may tame transplant complication
Disease control Recruiting nowThis study tests a new drug called gecacitinib (jaktinib) combined with steroids as a first treatment for people with moderate to severe graft-versus-host disease (GVHD) after a stem cell transplant. About 35 adults who have recently received a transplant and started steroids wit…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Timing is everything: new study aims to reduce transplant complications
Disease control Recruiting nowThis study looks at whether changing when stem cells are given during a cord blood transplant can lower the chance of a serious complication called graft-versus-host disease (GVHD). About 134 people with blood cancers who need a transplant will take part. The goal is to find a be…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: PHASE3 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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New hope for transplant patients: drug combo may tame deadly immune attack
Disease control Recruiting nowThis study tests a drug called ruxolitinib for treating acute graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body after a bone marrow transplant. About 98 adults with moderate to severe GVHD will receive either ruxolitinib alone or wi…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: John Levine • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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Toothbrush vs. transplant complication: can a simple cleaning prevent a deadly side effect?
Prevention Recruiting nowThis study tests whether a dental cleaning shortly after a stem cell transplant can prevent chronic graft-versus-host disease (GVHD), a serious condition where donor cells attack the patient's body. About 45 adults receiving a stem cell transplant for blood cancer will get a post…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Prevention
Last updated May 14, 2026 12:06 UTC
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Ancient heat therapy takes on transplant complication
Symptom relief Recruiting nowThis study tests whether moxibustion, a traditional Chinese medicine technique that burns herbs near the skin, can help people with severe graft-versus-host disease (GVHD) after a stem cell transplant. About 42 patients who have not responded to steroids will receive standard sec…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: PHASE2 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Symptom relief
Last updated May 12, 2026 13:44 UTC
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Exercise may tame steroid side effects in transplant patients
Symptom relief Recruiting nowThis study tests whether a home-based aerobic and resistance exercise program is feasible for adults with graft-versus-host disease (GVHD) who are starting high-dose steroids after a stem cell transplant. The goal is to see if exercise can help manage complications like high bloo…
Matched conditions: ACUTE GRAFT-VERSUS-HOST DISEASE
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated May 04, 2026 16:21 UTC