ACUTE CORONARY SYNDROMES

This study tests whether adding extra support from nurses, dietitians, and pharmacists to standard follow-up helps heart attack patients reach their LDL cholesterol goals. About 230 adults who had a recent heart attack will be randomly assigned to usual care or the extra team-bas…

This study compares two blood thinners, bivalirudin and heparin, in over 5,000 heart patients who are at high risk of bleeding and need a procedure to open blocked arteries (PCI). The goal is to see if bivalirudin reduces serious complications like death, heart attack, stroke, or…

This study tests whether starting three cholesterol-lowering drugs (including bempedoic acid) early during a heart attack hospital stay works better than standard care. About 600 adults hospitalized for a heart attack will receive either the triple therapy or usual treatment. The…

This study will observe 500 adults with stable or unstable heart disease who receive a laser treatment to clear hardened or blocked arteries during a standard heart procedure. The goal is to track how well the laser works and how safe it is in real-world use. Participants will be…

This study looks at whether having non-medical teams (like firefighters or paramedics) perform an ECG on people with heart attack symptoms leads to faster hospital care compared to when a doctor-led team does the ECG. Researchers will review records of 350 adults who called emerg…

This study tests whether teaching patients who have had a heart attack about the importance of lowering their LDL cholesterol helps them reach recommended goals. About 240 patients from 24 hospitals will take part. Half of the hospitals will provide the extra education, while the…

This study develops and tests a privacy-preserving AI system that reads de-identified patient admission notes to classify four types of coronary syndromes (heart attack types and chronic heart disease). The tool is evaluated across multiple hospitals and an English dataset to see…