Could dropping aspirin early after stent surgery be safer?

This trial investigates whether patients with acute coronary syndrome can safely stop taking aspirin soon after a heart stent procedure and continue with only a potent antiplatelet drug (ticagrelor or prasugrel). The standard approach is to take both aspirin and a P2Y12 inhibitor for 12 months. The study aims to see if early aspirin discontinuation reduces bleeding complications without increasing the risk of heart attacks, stent clots, or death. About 1,900 participants who had successful ultrasound-guided stent placement will be randomly assigned to either early single therapy or standard dual therapy and followed for one year.