ACNE VULGARIS

This study tests three gels for mild-to-moderate acne: a standard antibiotic-retinoid cream, the same cream plus a steroid, and a new gel made from stem-cell secretions. About 189 people aged 15-40 will use one of the gels for 8 weeks. Researchers will count pimples, check skin q…

This study tests two different gels—metronidazole and clindamycin—to see which works better for moderate acne. About 60 adults aged 18 to 35 will apply the gel twice a day for 12 weeks. Doctors will check their acne at the start and after 4, 8, and 12 weeks to measure improvement…

This study tests a new gel made with spironolactone against a standard acne gel (adapalene) in 40 people with mild to moderate acne. Each person will use the spironolactone gel on one side of their face and the adapalene gel on the other, so the results can be compared directly. …

This study tests a prescription gel called CABTREO in 100 children aged 9 to 11 with moderate to severe acne. The gel contains three medicines to fight acne bacteria, unclog pores, and reduce inflammation. Researchers will check for side effects and measure how much acne improves…

This study tests a cream called clascoterone for treating moderate to severe acne. About 692 people aged 12 and older will apply the cream or a placebo to their face twice daily for 12 weeks. The goal is to see if the cream clears acne better than a placebo.

This early-stage study tests a new drug called HB0043 in 21 adults with moderate to severe acne. The drug is a bispecific antibody that targets two inflammatory pathways (IL-17A and IL-36R) thought to drive acne. The main goal is to see if it safely reduces acne lesions and impro…

This study compares a new topical gel containing dutasteride to a standard triple-combination gel (clindamycin, benzoyl peroxide, adapalene) for treating facial acne in adults over 18. Researchers will measure how well each treatment clears acne lesions and improves quality of li…

This study tests a new cream called KR230109 in 180 people aged 18 to 40 with mild to moderate acne. Half will get the cream, half a placebo, and researchers will check if it reduces pimples and blackheads over 12 weeks. The goal is to see if the cream is safe and works better th…

This study tests whether taking oral probiotics for 12 weeks can reduce acne lesions and lower inflammation in people with moderate acne. Researchers will compare probiotics to a placebo in 64 Pakistani participants aged 15-35. The goal is to find a safe, antibiotic-free way to m…

This study looks at whether certain fat molecules (ceramides and S1P) in the blood are different in people with acne compared to healthy people. Researchers will collect blood samples from 80 participants (40 with acne, 40 without) and measure these molecules. The goal is to lear…