ACNE VULGARIS

This study compared two oral medications—metformin and doxycycline—for treating moderate to severe acne. Researchers enrolled 68 participants aged 12-40 and followed them for 12 weeks to see which medication better reduced acne lesions and improved skin appearance. The goal was t…

This study aimed to see if taking probiotic supplements could reduce levels of a specific protein (LRG1) linked to inflammation in people with mild to moderate acne. It involved 50 adult participants and measured changes in this marker, acne severity, and how satisfied patients f…

This study tested whether a new injectable drug called imsidolimab could safely reduce acne breakouts. About 123 teenagers and adults with moderate to severe facial acne received either the drug or a placebo (dummy shot) over 20 weeks. Researchers counted pimples and assessed ski…

This study tested how well and how safely the prescription acne cream Winlevi works for people with darker skin tones (Fitzpatrick types IV-VI). It involved 10 participants with moderate to severe facial acne who used the cream for 16 weeks. The main goal was to see how many peop…

This study tested if adding a traditional ear acupressure technique to a standard acne gel (0.1% adapalene) works better than the gel alone. It involved 64 adults aged 18-35 with mild to moderate acne. Researchers measured changes in acne severity, number of pimples, and quality …

This study tested whether a new generic version of a prescription acne gel works as well as the established brand-name product. Over 1,000 teenagers and adults with moderate acne used either the new gel, the brand-name gel, or a placebo gel for 12 weeks. Researchers measured chan…

This study tested a new treatment for mild to moderate acne that uses ultrasound waves to help push a sugar-water solution deeper into the skin. The goal was to see if this method could reduce inflammation and improve acne symptoms. The trial involved 115 young adults aged 18-30 …

This study looked at using two prescription acne creams together in a way that mimics real-life use. Twenty people with moderate to severe facial acne used Winlevi cream alongside adapalene 0.3% gel for 16 weeks. Researchers checked how many people achieved clear or almost clear …

This early-stage study tested the safety and early effects of a new topical medicine, PF-07905428, for acne. It involved 52 healthy adults and people with moderate to severe acne, who applied the gel to their face or back daily for up to 28 days. The main goal was to see if the t…

This study tested a new topical gel called IDP-126 for treating moderate to severe acne. It directly compared the new gel to a commonly used treatment, Epiduo Forte, and a placebo gel. The 12-week trial involved 686 participants aged 12 and older to see which treatment was more e…

This study tested whether a specific facial moisturizer is safe and helpful for people with mild to moderate acne. Over four weeks, 47 participants used the moisturizer while continuing their regular acne treatments. Doctors and the participants themselves checked for changes in …