ACNE VULGARIS

This study tested a combination of two acne treatments—Winlevi (a hormone-blocking cream) and adapalene 0.3% gel—to see how well they work together in real-life use. Twenty people with acne vulgaris used both treatments for 16 weeks. The main goal was to see how many achieved cle…

This study tested a cream called Winlevi on 10 people with darker skin tones (Fitzpatrick types IV, V, VI) who have acne. The main goal was to see how many patients had clear or almost clear skin after 16 weeks of treatment. The study was completed and focused on a group often le…

This study looked at whether applying dextrose (a type of sugar) through the skin using ultrasound waves (phonophoresis) can help treat mild to moderate acne. 115 people aged 18 to 30 with acne took part. The goal was to see if this treatment reduces acne severity and lesion coun…

This study tested a new acne gel called IDP-126 against a standard treatment (Epiduo Forte) and a placebo gel. About 686 people with moderate to severe facial acne applied one of the gels daily for 12 weeks. Researchers measured how much acne lesions decreased and how many people…

This study tested a new drug called imsidolimab for people with moderate to severe acne. 123 participants received either the drug or a placebo. The main goal was to see if the drug reduced the number of pimples and inflamed spots on the face after 12 weeks.

This study tested a dapsone gel against a placebo gel in 100 adults with mild-to-moderate acne. Participants applied the gel once daily for 8 weeks. Researchers measured acne severity, redness, oiliness, and quality of life to see if the gel helps improve skin and confidence.

This study tested whether oral metformin, a common diabetes medication, can treat moderate to severe acne. Researchers compared it to doxycycline, a standard antibiotic for acne. Sixty-eight participants took either metformin twice daily or doxycycline once daily for 12 weeks, an…

This study tested whether a facial moisturizer is gentle and effective for people with mild to moderate acne. 47 participants used the product for 4 weeks. Researchers checked skin dryness, redness, and overall appearance, and participants reported how their skin felt. The goal w…

This study looked at whether taking probiotics can reduce a protein in the blood (LRG1) that is linked to acne inflammation. Fifty adults with mild to moderate acne took probiotics, and researchers measured changes in their acne severity and satisfaction. The goal was to see if i…

This study tested whether a generic tretinoin gel works as well as the brand-name Retin-A Micro for treating acne. Over 1,000 people aged 12 to 40 with mild to moderate acne took part. Researchers measured changes in pimple and blackhead counts to see if the two treatments were e…

This early-stage study tested a new topical medicine (PF-07905428) for acne. It included 52 healthy volunteers and people with moderate to severe acne, aged 18 to 40. The medicine was applied daily for 2 to 4 weeks. The main goal was to check safety and how the body processes the…

This study tested whether adding a non-invasive ear acupressure technique to a standard acne cream (adapalene) helps clear pimples better than the cream alone. Sixty-four people with mild to moderate acne took part. Researchers measured changes in acne severity and lesion counts …