Generic acne gel put to the test in large trial
NCT ID NCT07469228
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 trial compared a generic tretinoin gel (0.04%) to the brand-name RETIN-A MICRO for treating acne vulgaris. Over 1,000 participants aged 12 to 40 with mild to moderate acne applied the gel daily for 12 weeks. The goal was to see if the generic version works just as well and is as safe as the original.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tretinoin gel microsphere, 0.04%
- What this could lead to
- If successful, this could show that the generic tretinoin gel works as well as the brand-name version for treating acne.
- What could go wrong
- This is an early Phase 1 trial focused on equivalence, not a new breakthrough. Results may not confirm the generic is as effective or safe as the reference drug.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sun Pharmaceutical Industries, Inc.
Hawthorne, New York, 10532, United States
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