New acne gel shows promise in Head-to-Head trial
NCT ID NCT04892706
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 40 times
Summary
This Phase 2 trial tested a new acne gel called IDP-126 against a standard gel (Epiduo Forte) and a placebo gel in 686 people aged 12 and older with moderate to severe acne. Participants applied the gel once daily for 12 weeks. Researchers measured changes in acne lesion counts and overall skin clarity to see if the new gel works better.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Bausch Site 101
Manhattan Beach, California, 90266, United States
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Bausch Site 102
Tampa, Florida, 33607, United States
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Bausch Site 103
Brighton, Massachusetts, 21350, United States
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Bausch Site 104
West Palm Beach, Florida, 33401, United States
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Bausch Site 105
Boynton Beach, Florida, 33437, United States
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Bausch Site 106
San Diego, California, 92123, United States
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Bausch Site 107
Gresham, Oregon, 97030, United States
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Bausch Site 108
Las Vegas, Nevada, 89148, United States
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Bausch Site 109
Dublin, Ohio, 43016, United States
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Bausch Site 110
Fremont, California, 94538, United States
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Bausch Site 111
Austin, Texas, 78759, United States
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Bausch Site 112
San Diego, California, 92123, United States
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Bausch Site 113
Saint-Jérôme, Quebec, J7Z 7E2, Canada
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Bausch Site 114
Nashville, Tennessee, 37215, United States
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Bausch Site 115
Peterborough, Ontario, K91 5K2, Canada
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Bausch Site 116
Rockville, Maryland, 20850, United States
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Bausch Site 117
Oklahoma City, Oklahoma, 73112, United States
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Bausch Site 118
Rogers, Arkansas, 72758, United States
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Bausch Site 119
New York, New York, 10022, United States
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Bausch Site 120
New Brighton, Minnesota, 55112, United States
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Bausch Site 121
Metairie, Louisiana, 70006, United States
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Bausch Site 122
West Palm Beach, Florida, 33406, United States
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Bausch Site 123
Pflugerville, Texas, 78660, United States
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Bausch Site 124
Newnan, Georgia, 30263, United States
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Bausch Site 125
Markham, Ontario, L3P 1X3, Canada
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Bausch Site 126
Clearwater, Florida, 33761, United States
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Bausch Site 127
Boise, Idaho, 83704, United States
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Bausch Site 128
San Diego, California, 92123, United States
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Bausch Site 129
Louisville, Kentucky, 40241, United States
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Bausch Site 130
Waterloo, Ontario, N2J 1C4, Canada
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Bausch Site 132
Houston, Texas, 77098, United States
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Bausch Site 133
New York, New York, 10075, United States
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Bausch Site 134
Bryant, Arkansas, 72022, United States
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Bausch Site 135
North Miami Beach, Florida, 33162, United States
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Bausch Site 136
Kortrijk, Belgium
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Bausch Site 137
Spokane, Washington, 99202, United States
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Bausch Site 138
Winnipeg, Manitoba, R3M 3Z4, Canada
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Bausch Site 139
Mandeville, Louisiana, 70448, United States
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Bausch Site 140
Maldegem, Belgium
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Bausch Site 141
Oakville, Ontario, L6J 7W5, Canada
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Bausch Site 142
High Point, North Carolina, 27262, United States
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Bausch Site 143
Sanford, Florida, 32771, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
IDP-126 gel (a combination acne treatment applied to the skin once daily)
What this could lead to
If it works, this could offer a new once-daily gel option for treating moderate to severe acne.
What could go wrong
This is a Phase 2 trial, so results are still early. The gel may not prove more effective than existing treatments, and side effects like skin irritation are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.