New light therapy could zap stubborn acne without pills
NCT ID NCT05080764
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a treatment called photodynamic therapy (PDT) for adults with moderate to severe acne. A gel called Ameluz® is applied to the face, then activated with a special red light. The goal is to see if this combination reduces acne lesions better than a placebo. About 126 adults are taking part in this phase II trial.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ameluz® (BF-200 ALA) with red light photodynamic therapy
What this could lead to
If successful, this could offer a new, non-antibiotic treatment option for adults with stubborn moderate to severe acne.
What could go wrong
This is a mid-stage trial with only 126 participants, so results may not apply to everyone. Photodynamic therapy can cause temporary redness, swelling, and pain during treatment.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACNE VULGARIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Austin Institute for Clinical Research Inc.
Pflugerville, Texas, 78660, United States
-
Clinical Research Center of the Carolinas
Charleston, South Carolina, 29407, United States
-
Cosmetic Laser Dermatology
San Diego, California, 92121, United States
-
DelRicht Research
Baton Rouge, Louisiana, 70809, United States
-
DermResearch PA
Austin, Texas, 78759, United States
-
Dermatology Associates PA of the Palm Beaches
Delray Beach, Florida, 33445, United States
-
First OC Dermatology
Fountain Valley, California, 92708, United States
-
ForCare Clinical Research
Tampa, Florida, 17033, United States
-
Skin Search of Rochester, Inc
Rochester, New York, 14623, United States