Could vitamin d help clear acne? new trial tests the idea
NCT ID NCT06141330
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This completed trial tested whether adding vitamin D supplements to standard acne treatment (azithromycin and a topical retinoid) improves acne more than standard treatment alone. Fifty-eight people aged 13 to 40 with acne vulgaris took part. The main goal was to see if the combination led to better skin improvement after two months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin D supplements
- What this could lead to
- If it works, this could point toward adding vitamin D to standard acne treatment for better results.
- What could go wrong
- This is a small, completed trial with only 58 participants. The results may not apply to everyone, and vitamin D may not provide extra benefit beyond standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
58 people
The number who actually took part.
- Started
-
Feb 2024
- Finished
-
Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
13 to 40 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals aged between 13 and 40 years with diagnoses of Acne vulgaris are included. Exclusion Criteria: * Individuals currently undergoing treatment for polycystic ovary syndrome (PCOs) * Those with obesity * Individuals employing vitamin supplementation * Those under the influence of topical or systemic steroids and acne treatment in the last 2 months.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acne vulgaris are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hitec-Ims
Islamabad, Punjab Province, 47080, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Acne may signal hidden hormonal disorder in young women
- Hormone tests may reveal who benefits most from acne drug
- Blood pressure drug takes on antibiotics for Women's acne
- Can radiofrequency waves outperform acne gels?
- Can adding a chemical peel to microneedling erase acne scars better?
- Can a beam of light boost acne treatment?