Ventricular tachycardia

This trial tests whether a wearable ECG patch called MEMO Patch Plus can detect clinically significant arrhythmias in adults hospitalized with acute heart failure. Participants wear the patch for up to 14 days in the hospital and again for up to 14 days after discharge. The study…

This trial tests whether a new physical technique, the reverse vagal maneuver, can restore normal heart rhythm in adults with paroxysmal supraventricular tachycardia (PSVT) more effectively than the standard modified Valsalva maneuver. Participants are randomly assigned to one of…

This trial tests a special implantable cardioverter-defibrillator (ICD) that uses a single lead to sense both heart chambers, aiming to detect atrial fibrillation and other arrhythmias early. It includes 56 people who need a single-chamber ICD and are in normal sinus rhythm at th…

This study tested whether using a CT scan before heart ablation can make the procedure faster and safer for people with ventricular tachycardia, a fast heart rhythm that can be life-threatening. 119 adults who had a prior heart attack and an implanted defibrillator were randomly …

This early study tested a new device called the FieldForce™ Ablation System in 34 people with ventricular arrhythmias (dangerous heart rhythms). The device uses pulsed electric fields to destroy the small areas of heart tissue causing the problem. The main goal was to see if the …

This study tested a wearable defibrillator patch (the Jewel) in 18 adults who were already scheduled for a heart procedure. The patch was used to deliver a shock to stop dangerous heart rhythms that could lead to sudden cardiac arrest. The goal was to see how often the patch coul…

This trial tested a new ablation catheter (DiamondTemp) against the current standard (Tacticath/Tactiflex) for treating ventricular tachycardia (VT), a life-threatening fast heart rhythm. 61 adults with VT who needed ablation took part. The goal was to see if the new catheter is …

This study tested a new freezing method (cryoablation) to treat a fast, dangerous heart rhythm called ventricular tachycardia. 64 adults who had not responded well to medication took part. The goal was to see if freezing the small area causing the problem could safely stop the rh…

This study tested whether permanent pacemakers can be safely implanted using only ultrasound (transthoracic echocardiography) instead of traditional X-ray guidance. Thirty-one adults with arrhythmias who needed a pacemaker took part. The goal was to see if the procedure could be …

This study tested whether a single dose of dantrolene, a muscle relaxant, could reduce the risk of dangerous heart rhythms in 68 people with structural heart disease who were scheduled for a procedure to treat ventricular tachycardia. Participants received either dantrolene or a …

This pilot study tested a procedure called bilateral sympathectomy, which cuts certain nerves to the heart, in 45 Chagas disease patients with implantable defibrillators (ICDs) who had frequent dangerous heart rhythms. Participants were randomly assigned to receive the nerve-cutt…

This study tested a new computer simulation, called a 'virtual heart,' to help doctors find the best spots to burn heart tissue (ablation) in patients with ventricular tachycardia (VT) caused by prior heart attacks. Ten adults with VT and scarred heart muscle were enrolled. The a…

This study tested whether using cardiac MRI to guide ablation (a procedure that destroys small areas of heart tissue) can improve outcomes for people with ventricular tachycardia, a dangerous fast heart rhythm. 104 adults with structural heart disease were randomly assigned to on…

This study tested a new type of wire (lead) for implantable heart devices that deliver shocks to stop dangerous fast heart rhythms. Researchers checked how safe and effective the lead was in 998 people who needed a defibrillator or heart failure device. The lead was placed in a s…

This trial tests whether a wearable patch called MEMO Patch V2 can detect heart rhythm disorders (arrhythmias) more effectively than the standard 24-hour Holter monitor. Adults with symptoms like palpitations or dizziness, or those who have had a stroke of unknown cause, will wea…

This study investigates whether an Apple Watch can accurately detect heart rhythm problems (arrhythmias) in children aged 6 to 21 who are already scheduled for standard heart monitoring. Researchers will compare the watch's ECG and heart rate readings to those from conventional c…

This study tested a new non-invasive tool called ECG-Imaging that uses many electrodes on the body to create a 3D map of the heart's electrical activity. The goal was to see if it can more accurately locate the source of heart rhythm problems compared to a standard ECG. 362 parti…

This trial compares two standard local anesthetics given during pacemaker or defibrillator surgery: a mixture of lidocaine and bupivacaine versus lidocaine alone. Researchers want to see if the mixture reduces postoperative pain and the need for narcotic painkillers. About 350 pe…

This study tested a nasal spray called etripamil for people with a condition that causes sudden rapid heartbeats (PSVT). Participants, who had been in earlier studies, used the spray themselves at home to stop an episode. The main goal was to see if it was safe and easy to use ou…

This study looked at whether a 12-week virtual exercise program could help women with cardiac implantable electronic devices (CIEDs) improve their physical fitness, quality of life, and mental health. Twenty women took part, doing either high-intensity interval training (HIIT) or…

This study looks at children and adolescents aged 6 to 16 with inherited arrhythmias, such as long QT syndrome, to see if a controlled exercise test on a treadmill reflects their actual heart rate and activity levels during daily life. Participants will complete a routine exercis…

This study aims to establish national reference levels for radiation exposure during X-ray guided procedures to correct heart rhythm disorders, such as pacemaker insertions and ablations. Researchers will collect radiation dose data from over 4,000 adult patients undergoing these…

This study tests whether wearing a heart monitor for 14 days can detect dangerous heart rhythms in people with mitral valve prolapse (a common heart valve condition) better than the usual 24-hour test. About 60 adults with MVP will wear a patch monitor for two weeks. The goal is …

This study looks at how inherited heart rhythm problems (like Long QT Syndrome) and heart muscle diseases (like Hypertrophic Cardiomyopathy) affect the quality of life and physical activity of children aged 6 to 18. Researchers will compare 107 children with these conditions to 1…

This study looked at whether it's safe to skip the defibrillation test when implanting a subcutaneous implantable cardioverter-defibrillator (S-ICD). The test involves purposely triggering a dangerous heart rhythm to make sure the device can stop it. About 965 people took part. T…

This study tested whether a CT scan before a heart procedure could help doctors better target the source of a dangerous heart rhythm called ventricular tachycardia. 23 people who had a prior heart attack and needed catheter ablation took part. The approach aimed to see if using C…

This study looked at whether a special mapping tool called vMap can help doctors perform heart ablations more efficiently for people with irregular heartbeats (arrhythmias). Researchers tracked 112 patients to see if using vMap reduced procedure time and improved success rates. T…

This study used computer simulations to compare three types of radiation (photons, protons, and carbon ions) for treating a dangerous heart rhythm called ventricular tachycardia. Researchers created treatment plans for 23 patients who were already scheduled for standard catheter …

This study tested whether a special pacing technique in the heart's right ventricle can more accurately predict where certain rapid heartbeats originate, compared to standard ECG criteria. Researchers enrolled about 200 patients undergoing catheter ablation for ventricular arrhyt…

This completed study looked at 60 heart failure patients with reduced pumping function and dangerous heart rhythms. Researchers compared metabolic profiles between those with ischemic (blocked arteries) and non-ischemic (other causes) heart disease. By analyzing blood samples, th…

This study looked at 537 people with myotonic dystrophy type 1 to understand their risk of serious heart rhythm problems, including sudden cardiac arrest. Researchers tracked participants for two years to see how often these events happened and what factors might predict them. Th…

This completed registry study followed over 5,000 people with heart rhythm disorders who received Abbott devices during standard procedures. The goal was to collect real-world data on safety and how well the devices work. No new treatments were tested; instead, the study observed…

This completed study looked at how the heart medication amiodarone behaves in children aged 0 to 18 with heart rhythm disorders. Researchers took blood samples from 57 children to measure drug levels and understand how the body processes it. The goal was to find the best dose for…

This study used a special brain imaging technique called near-infrared spectroscopy to see how the brain responds to pain and sounds while people are under general anesthesia. 44 healthy volunteers aged 12-30 were given either a painkiller (remifentanil) or a placebo. The goal wa…