Venous thromboembolism

This study looked at the safety and effectiveness of Pradaxa oral pellets in children aged 3 months to 12 years who had blood clots (venous thromboembolism). The goal was to see how often bleeding or new clots occurred in real-world use. Only 5 children were enrolled before the s…

This study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…

This phase 3 trial tested a new drug, abelacimab, against a standard blood thinner (dalteparin) to prevent dangerous blood clots from returning in people with gastrointestinal or genitourinary cancers. The study enrolled 417 adults with advanced cancer and a recent clot. It was t…

This study tested whether checking blood clotting levels every week with a small finger-prick device is better than the usual monthly lab test for elderly nursing home residents on blood thinners. The goal was to see which method keeps patients in the safe therapeutic range longe…

This study tested a new blood thinner, abelacimab, against the standard drug apixaban in about 1,150 people with cancer who had a blood clot. The goal was to see which drug better prevented new clots and caused less bleeding. The study was stopped early, but the results may still…

This study tested a special PET scan tracer to see if it can find fresh blood clots in people with pulmonary embolism (PE) or deep vein thrombosis (DVT). Six adults with confirmed clots received the tracer within 72 hours of diagnosis. The goal was to compare the PET images with …

This study tested a new oral blood thinner called SHR2285 in people having knee replacement surgery. The goal was to see if it could prevent dangerous blood clots as well as the standard injection enoxaparin. The trial was planned for 64 participants but was terminated early, so …

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…

This study looked at how platelets (small blood cells) might cause long-term complications like leg swelling or breathing problems after a blood clot. Researchers measured specific receptors on platelets in 44 patients to see if they were linked to these lasting issues. The goal …