New pill aims to stop blood clots after knee surgery – but trial halted early
NCT ID NCT05203705
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new oral blood thinner called SHR2285 in people having knee replacement surgery. The goal was to see if it could prevent dangerous blood clots as well as the standard injection enoxaparin. The trial was planned for 64 participants but was terminated early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SHR2285 tablet
- What this could lead to
- If successful, SHR2285 could offer a new oral option to prevent dangerous blood clots after knee replacement surgery.
- What could go wrong
- This was an early phase 2 trial that was terminated, so results are limited. It is unclear if SHR2285 is safer or more effective than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Perking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China