New pill aims to stop blood clots after knee surgery – but trial halted early
NCT ID NCT05203705
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new oral blood thinner called SHR2285 in people having knee replacement surgery. The goal was to see if it could prevent dangerous blood clots as well as the standard injection enoxaparin. The trial was planned for 64 participants but was terminated early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SHR2285 tablet
What this could lead to
If successful, SHR2285 could offer a new oral option to prevent dangerous blood clots after knee replacement surgery.
What could go wrong
This was an early phase 2 trial that was terminated, so results are limited. It is unclear if SHR2285 is safer or more effective than existing treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Perking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China