Varicocele
MONDO:0001498A condition characterized by the dilated tortuous veins of the spermatic cord with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.
Also known as: scrotal varices, scrotum varicose disease, varicose disease of scrotum
19 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Smartphone Follow-Up could replace hospital stays after common surgeries
Disease control Not yet recruitingThis study tests whether sending patients home on the same day of surgery, with follow-up care via phone calls, home visits, and a mobile app, is as safe and less costly than keeping them in the hospital overnight. The trial includes adults in Uganda having low-risk procedures su…
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Surgery for enlarged scrotum veins may boost sperm health by reducing immature cells
Disease control Not yet recruitingThis study looks at how surgery to fix varicocele—enlarged veins in the scrotum—affects the number of immature sperm cells in semen. Infertile men aged 20 to 45 with varicocele will have a microsurgical procedure to tie off the abnormal veins. Their semen will be tested before su…
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Massage therapy could boost sperm quality in men with varicocele
Disease control Not yet recruitingThis study tests whether a type of abdominal massage called visceral osteopathic manual therapy can improve sperm quality and blood flow in men with varicocele, a condition where veins in the scrotum become enlarged and can cause infertility. Thirty-two men aged 18-45 will either…
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New surgical twist may boost fertility after varicocele repair
Disease control Not yet recruitingThis study tests a more thorough varicocele surgery that strips away extra veins, compared to the standard method. About 160 infertile men with varicocele will be randomly assigned to one of the two procedures. The goal is to see if the extended stripping reduces the chance of va…
Phase: NA • Sponsor: Benha University • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Sedative showdown: dexmedetomidine vs ketamine for varicocele surgery
Symptom relief Not yet recruitingThis study compares two sedative drugs, dexmedetomidine and ketamine, given before spinal anesthesia for varicocele surgery. The goal is to see which one provides better sedation and fewer side effects. The trial will involve 58 men aged 18 to 40.
Phase: PHASE4 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Testicle blood flow may predict fertility surgery success
Knowledge-focused Not yet recruitingThis study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Blood flow in varicocele linked to sperm health, new study aims to prove
Knowledge-focused Not yet recruitingThis study looks at 100 men with varicoceles (enlarged veins in the scrotum) to see if the amount of backward blood flow affects sperm quality. Participants will have ultrasound and semen tests before and 3 months after varicocele repair surgery. The goal is to better understand …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC