Varicella zoster infection

This study tests a new chickenpox vaccine called NBP608 in about 780 children aged 1 to 12 years. The vaccine is compared to licensed vaccines to see how well it triggers immunity and if it is safe. Children receive one or two shots, and researchers monitor their immune response …

This study tests a new chickenpox vaccine in 300 healthy children aged 1 to 12 years. All children will receive one dose of the vaccine. Researchers will check if the vaccine triggers a strong immune response and is safe to use.

This study tests a new mRNA vaccine called SYS6017 to prevent shingles, a painful rash caused by the chickenpox virus. About 800 healthy adults aged 40 and older will receive either the new vaccine, a placebo, or an existing shingles vaccine. Researchers will check how well the v…

This phase 2 trial tests a new mRNA vaccine called IN001 for preventing shingles in healthy adults aged 50 to 79. Researchers will compare three dose levels of IN001 against the existing Shingrix vaccine to see how safe and effective they are. The study involves 480 participants …

This study investigates whether two common vaccines—the shingles vaccine (RZV) and an RSV vaccine (RSVPreF3)—can slow the buildup of fatty plaque in the coronary arteries. The trial enrolls adults aged 50 and older who are at risk for cardiovascular events. Participants receive e…

This trial tests whether a single dose of a live-attenuated shingles vaccine can effectively boost immunity in adults aged 50 and older who have already received the recombinant shingles vaccine. The study measures antibody and cellular immune responses after the booster. If it w…

This study tests an investigational vaccine that combines protection against measles, mumps, rubella, and chickenpox (varicella) in a single shot. It will be given as a second dose to healthy children aged 4 to 6 years who have already received a first dose of a similar vaccine. …

This study tests a new shingles vaccine in 135 healthy adults aged 50 and older. Researchers will compare the immune response and safety of the new vaccine against an existing one to find the best dose. The goal is to prevent shingles, a painful rash caused by the chickenpox viru…

This study tests whether an extra dose of the shingles vaccine (Shingrix) can boost immunity in people who have had a solid-organ transplant, like a kidney or liver. About 30% of transplant patients still get shingles after the standard two-dose vaccine, likely due to immune-supp…

This study looks at whether the shingles vaccine can prevent shingles and improve survival in 500 lung cancer patients. Participants will either receive the vaccine or not, and researchers will track shingles cases and survival rates over time. The goal is to see if the vaccine o…

This study tests a special gel applied to the skin to see if it can quickly reduce pain from shingles. Thirty adults with shingles-related pain will receive a single application of the gel. Researchers will measure pain levels before and after application, focusing on relief with…

This study tests whether dexamethasone palmitate, a steroid, can better relieve shingles pain and prevent long-term nerve pain compared to standard care. About 954 adults with shingles rash and severe pain will receive the drug by injection or infusion. Researchers will track pai…