MRNA vaccine aims to prevent shingles in older adults

NCT ID NCT07205796

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new mRNA vaccine called IN001 for preventing shingles in healthy adults aged 50 to 79. Researchers will compare three dose levels of IN001 against the existing Shingrix vaccine to see how safe and effective they are. The study involves 480 participants and will measure immune responses and side effects over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Herpes Zoster IN001 mRNA Vaccine (IN001)

What this could lead to

If successful, this could lead to a new mRNA-based shingles vaccine that is safer or more effective than current options.

What could go wrong

This is an early phase 2 trial with only 480 participants, so results may not apply to everyone. The vaccine could cause side effects or fail to show strong enough immune response.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chickenpox DNA Virus Infections Herpesviridae infectious disease Infections Skin Diseases, Viral skin disorder skin disorder caused by infection Varicella Zoster Virus Infection viral infectious disease herpes zoster prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••