Urethral disorder

This study compares two surgical methods to repair a short (up to 2 cm) narrowing in the bulbar urethra. One technique removes the scarred section and reconnects healthy ends; the other uses a graft from the lining of the testicle to widen the stricture. 94 men aged 18-50 with no…

This study will test whether using wipes with a special antibacterial solution (chlorhexidine gluconate) before surgery can reduce bacteria on the skin better than standard cleaning. It involves 40 men with urethral stricture who are scheduled for reconstructive surgery. Research…

This study tests whether a single dose of tranexamic acid (TXA), a drug that helps blood clot, can reduce blood loss during urethral reconstruction surgery. Forty adults having this surgery will be randomly assigned to receive TXA or standard care. Researchers will compare change…

This study investigates whether giving lidocaine or dexmedetomidine through a vein during urethral reconstruction surgery can lower pain right after surgery and reduce the chance of chronic pain lasting months later. About 80 adults scheduled for this surgery will receive one of …

This study will compare two laser surgeries (HoLEP and ThuLEP) for treating an enlarged prostate in 200 men aged 40-90. The goal is to see which procedure better preserves bladder control, avoids urethral narrowing, and maintains sexual function. Researchers will track outcomes l…

This study compares taking tamsulosin every day versus every other day in 288 men aged 40 and older with enlarged prostate and moderate-to-severe urinary symptoms. The goal is to see if the every-other-day schedule controls symptoms just as well while possibly causing fewer sexua…

This study looks at how age and sex influence pain before and after a first-time flexible cystoscopy (a thin tube inserted into the bladder). Researchers will ask 150 adults to rate their expected and actual pain using a simple 0-10 scale. The goal is to better understand who mig…