Urethral intrinsic sphincter deficiency
MONDO:0001721Also known as: intrinsic (urethral) sphincter deficiency [ISD]
3 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
New adjustable implant aims to stop leakage in women
Disease control Recruiting nowThis trial tests a device called Adjustable Continence Therapy (ACT) for women with stress urinary incontinence caused by a weak urethral sphincter. The implant has two balloons placed near the bladder neck that can be adjusted after surgery to improve control. The study will enr…
Phase: NA • Sponsor: Uromedica • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
-
Muscle fragments may fix bladder leaks
Symptom relief Recruiting nowThis early study tests whether injecting a patient's own muscle fibers into the bladder neck or urethra is safe for treating urinary incontinence. Ten adult women with incontinence due to a weak outlet will be monitored for side effects and changes in leakage over 12 months.
Phase: PHASE1, PHASE2 • Sponsor: Wake Forest University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC