Urethral intrinsic sphincter deficiency
MONDO:0001721Also known as: intrinsic (urethral) sphincter deficiency [ISD]
6 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New adjustable implant aims to stop leakage in women
Disease control Recruiting nowThis trial tests a device called Adjustable Continence Therapy (ACT) for women with stress urinary incontinence caused by a weak urethral sphincter. The implant has two balloons placed near the bladder neck that can be adjusted after surgery to improve control. The study will enr…
Phase: NA • Sponsor: Uromedica • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Muscle fragments may fix bladder leaks
Symptom relief Recruiting nowThis early study tests whether injecting a patient's own muscle fibers into the bladder neck or urethra is safe for treating urinary incontinence. Ten adult women with incontinence due to a weak outlet will be monitored for side effects and changes in leakage over 12 months.
Phase: PHASE1, PHASE2 • Sponsor: Wake Forest University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Let it fall? study tests if letting catheters drop out on their own is better than nurse removal
Symptom relief Recruiting nowThis study tests whether letting a bladder catheter fall out on its own (passive removal) is better than having a nurse pull it out (active removal) after urological surgery. 160 men will be randomly assigned to one method. Researchers will measure satisfaction, pain, and anxiety…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can videos and quizzes help patients better understand surgery?
Knowledge-focused Recruiting nowThis study tests a new method to help patients understand complex spine or prostate surgeries before they agree to them. Instead of just reading a form, patients watch multimedia content and answer questions to check their understanding. The goal is to see if this approach makes …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can AI match doctors? new study puts ChatGPT to the test on urology cases
Knowledge-focused Recruiting nowThis study looks at how well three AI models—ChatGPT, Gemini, and Deepseek—can diagnose and suggest treatments for urology diseases. Researchers will use 800 past patient records from four hospitals to check the AI's accuracy and usefulness. The goal is to understand if AI can he…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC