Can a simple drug make urethral surgery safer?

NCT ID NCT07501884

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single dose of tranexamic acid (TXA), a drug that helps blood clot, can reduce blood loss during urethral reconstruction surgery. Forty adults having this surgery will be randomly assigned to receive TXA or standard care. Researchers will compare changes in hemoglobin levels and other bleeding-related outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tranexamic acid (TXA)

What this could lead to

If it works, this could lead to a simple, safe way to reduce blood loss during urethral surgery, potentially improving recovery and reducing complications.

What could go wrong

This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. TXA also carries a small risk of blood clots, though participants with clotting history are excluded.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hemorrhage urethral disorder urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital

    Newark, New Jersey, 07103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••