Could a simple infusion during surgery stop pain before it starts?

NCT ID NCT07676942

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study investigates whether giving lidocaine or dexmedetomidine through a vein during urethral reconstruction surgery can lower pain right after surgery and reduce the chance of chronic pain lasting months later. About 80 adults scheduled for this surgery will receive one of the two drugs or a placebo. The goal is to see if these well-known, safe medications can improve recovery and prevent long-term pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine and dexmedetomidine

What this could lead to

If effective, these well-known drugs could become a standard way to prevent long-term pain after urethral surgery, reducing opioid use.

What could go wrong

This is a small, early-stage trial. The drugs may not reduce chronic pain more than placebo, and side effects like low blood pressure or slow heart rate are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuralgia Pain, Postoperative urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Department of Anesthesiology and Intensive Care, Centre of Postgraduate Medical Education

    Warsaw, 01-355, Poland