Urethral disorder

This phase 3 trial tested whether adding bevacizumab (Avastin) to standard chemotherapy (gemcitabine and cisplatin) helps people with advanced urinary tract cancer live longer. 506 patients with cancer that had spread or could not be removed by surgery took part. The study compar…

This registry follows 180 women receiving an artificial urinary sphincter for stress incontinence caused by a weak sphincter. Researchers measure how many become dry (using no pads or just one light pad) and how long that dryness lasts over 5 years. Participants also report on se…

This early-phase trial tested a combination of two chemotherapy drugs (gemcitabine and carboplatin) plus lenalidomide, a drug that blocks blood vessel growth in tumors, in 18 adults with advanced solid tumors, especially urothelial (bladder) cancer. The main goal was to find the …

This pilot study tested a bioengineered collagen scaffold as a substitute for the traditional mouth-tissue graft used in urethral stricture repair. Five adult men with a short urethral stricture (less than 3 cm) received the implant. The main goal was to see if the urethra stayed…

This study tested a special balloon coated with the drug paclitaxel to treat urethral stricture, a narrowing of the tube that carries urine out of the body. Sixteen men with recurrent strictures received the balloon treatment. The goal was to see if the device is safe and can hel…

This study tested whether a rapid 30-minute desktop test for gonorrhea and chlamydia could help doctors make better treatment decisions compared to the current standard (a gram stain). 98 adults with symptoms of urethritis or cervicitis took part. The goal was to see if the rapid…

This study compared two ways to treat a narrow urethra (the tube that carries urine out of the body) in 60 men aged 18 to 70. One method uses a laser, the other a cold knife. The goal was to see which works better at improving urine flow after 30 days. The findings could help sta…

This study tested whether a non-invasive magnetic brain stimulation technique (rTMS) can help adults with overactive bladder. Researchers measured changes in brain activity and bladder symptoms in 14 participants. The goal was to see if targeting specific brain regions could impr…

This study checks if men who had a treated urethritis infection still have signs of long-term inflammation and cell damage in their genital tract. Researchers measured a protein called elastase and markers of oxidative stress in semen 6 and 12 months after treatment. They compare…

This study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The go…