New balloon coated with drug may help men with narrowed urethra

NCT ID NCT03270384

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special balloon coated with the drug paclitaxel to treat urethral stricture, a narrowing of the tube that carries urine out of the body. Sixteen men with recurrent strictures received the balloon treatment. The goal was to see if the device is safe and can help prevent the stricture from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon

What this could lead to

If it works, this could offer a less invasive treatment option for recurrent urethral stricture, potentially reducing the need for repeat procedures.

What could go wrong

This was a very small early study with only 16 participants, so results may not apply to everyone. The drug coating (paclitaxel) could cause side effects, and the stricture might still come back.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chesapeake Urology

    Hanover, Maryland, 21076, United States

  • Metro Urology

    Woodbury, Minnesota, 55125, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • Urology of Virginia

    Virginia Beach, Virginia, 23462, United States