New balloon coated with drug may help men with narrowed urethra

NCT ID NCT03270384

Completed Disease control Sponsor: Urotronic Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a special balloon coated with the drug paclitaxel to treat urethral stricture, a narrowing of the tube that carries urine out of the body. Sixteen men with recurrent strictures received the balloon treatment. The goal was to see if the device is safe and can help prevent the stricture from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paclitaxel-coated balloon
What this could lead to: If it works, this could offer a less invasive treatment option for recurrent urethral stricture, potentially reducing the need for repeat procedures.
What could go wrong: This was a very small early study with only 16 participants, so results may not apply to everyone. The drug coating (paclitaxel) could cause side effects, and the stricture might still come back.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

URETHRAL STRICTURE

Contacts and locations

Locations

Chesapeake Urology

Hanover, Maryland, 21076, United States
Metro Urology

Woodbury, Minnesota, 55125, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
Urology of Virginia

Virginia Beach, Virginia, 23462, United States

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