Ureteral disorder

This phase 3 trial tested whether adding bevacizumab (Avastin) to standard chemotherapy (gemcitabine and cisplatin) helps people with advanced urinary tract cancer live longer. 506 patients with cancer that had spread or could not be removed by surgery took part. The study compar…

This early-phase trial tested a combination of two chemotherapy drugs (gemcitabine and carboplatin) plus lenalidomide, a drug that blocks blood vessel growth in tumors, in 18 adults with advanced solid tumors, especially urothelial (bladder) cancer. The main goal was to find the …

This study tested a special stent called MEMOKATH 051 in 13 adults with long-term ureter blockages who usually need a standard double J stent. The goal was to see how long the new stent lasts and how well it is tolerated over 3 years. Participants had the new stent placed during …

This study tested a new drug called enfortumab vedotin against standard chemotherapy in 608 adults with advanced bladder or urinary tract cancer that had spread or come back after prior treatment. The goal was to see if the new drug helped people live longer and slowed cancer gro…

This study tested whether a special ultrasound with a contrast dye (Definity) can detect kidney obstructions. Ten adults with a blocked kidney had ultrasound scans before and after surgery to relieve the blockage. The goal was to see if this method works as well as standard nucle…

This study looked at two methods for removing kidney stones: laser dusting (breaking stones into tiny pieces that pass naturally) and basket extraction (using a small wire basket to remove fragments). Researchers compared how well each method cleared stones, how much pain patient…

This study tested a modified Single-J ureteric stent designed to cause less discomfort than the standard Double-J stent after kidney stone surgery. 28 adults who already had a stent placed before surgery received the modified stent during their procedure. Researchers compared sym…

This study looked at 96 men who needed a temporary tube (stent) in their ureter after kidney stone surgery. Half got a standard stent, the other half got a new anti-reflux stent. Researchers checked sexual function, mood, and hormone levels over 8 weeks to see if the anti-reflux …

This study looked at 100 adults with large upper ureteric stones (over 10 mm) to compare two surgical techniques: one going down from the kidney (antegrade) and one going up from the bladder (retrograde). The goal was to see which method removes stones more completely and safely,…

This study tested whether barbed sutures (V-Loc) are safer and easier to use than standard polyglactin sutures (Vicryl) in minimally invasive kidney surgery for a blocked ureter. Forty adults aged 18 to 60 were randomly assigned to receive either barbed or standard sutures during…

This study tested whether ketorolac, a non-steroidal anti-inflammatory drug (NSAID), works as well as the opioid oxycodone for pain after kidney stone removal. 81 adults who had ureteroscopy and received a ureteral stent took part. For five days after surgery, they recorded their…

This study looked at 224 adults with kidney or ureter stones who needed a stent after surgery. Half got a silicone stent, half got a standard plastic stent. The goal was to see which type caused less pain and interference with daily life in the days and weeks after surgery.

This study compared two common surgeries for removing large kidney stones stuck in the upper ureter: ureteroscopic lithotripsy (URS) and laparoscopic ureterolithotomy (LU). Fifty-six adults with a single stone between 10-20 mm were randomly assigned to one procedure. Researchers …

This study looked at whether giving antibiotics before a kidney drainage procedure (called percutaneous nephrostomy) prevents urinary tract infections in cancer patients whose urinary tract is blocked by a tumor. Researchers reviewed records of 320 cancer patients who had the pro…

This study looked at 130 people treated for ureteral stones using two different sizes of ureteroscopes. Researchers measured how well each scope worked and how much stress the surgeon felt before and after the procedure. The goal is to find out if using a smaller or larger scope …

This completed registry followed 379 people who received a Boston Scientific ureteral stent to treat a blocked ureter. The goal was to see how well the stent worked and if it caused any serious side effects. Patients also reported on their quality of life. The study provides real…

This completed trial compared two surgical procedures for removing kidney stones: standard PCNL and mini-PCNL. The study enrolled 18 adults with stones 10-20mm and measured blood loss, complications, and recovery time. The goal was to see if the smaller incision approach offers a…