Toxic shock syndrome

MONDO:0001881

A rare acute life-threatening systemic bacterial noncontagious illness caused by exotoxins from bacteria of either the Streptococcus pyogenes or Staphylococcus aureus type. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.

Also known as: TSS, TSS, toxic shock syndrome, bacterial TSS, bacterial toxic-shock syndrome, shock syndrome (TSS), toxic, syndrome (TSS), toxic shock, toxic shock syndrome, toxic shock syndrome, (TSS)

224 clinical trials for this condition and its sub-types.

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Sub-types

Staphylococcal toxic-shock syndrome (1) Streptococcal toxic-shock syndrome (1)

Broader categories

Disease (618) Infectious disease (270) Bacterial infectious disease (85) Syndromic disease (24) Human disease (14) Commensal bacterial infectious disease (0) Disease by body system or component (0) Disease by etiologic mechanism (0) Disease of primarily extrinsic mechanism (0)

Trials to join now! 77 Not yet recruiting 45 Not yet finished but already full! 18 Completed 76 Terminated 8

Toxic shock syndrome

Sub-types

Broader categories

Can a simple urine test prevent kidney failure in sepsis?

Timing of dialysis in septic shock: early vs. delayed – study halted early

Could a common sedative save lives in septic shock?

Could a pill replace IV drips for septic shock? small trial halted early

New sedation approach may help septic shock patients breathe on their own sooner

Blood pressure experiment in sepsis halted early – kidney protection still unclear

Blood pressure drug study in septic shock halted early

Sticker shock: simple reminder may cut unnecessary IV antibiotic use