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Streptococcal toxic-shock syndrome

MONDO:0020544

Streptococcal toxic-shock syndrome (streptococcal TSS) is an acute disease mediated by the production of superantigenic toxins characterized by the sudden onset of fever and other febrile symptoms, pain, multisystem organ involvement and potentially leading to coma, shock and death due to a Streptococcus pyogenes infection.

Also known as: Streptococcus caused toxic shock syndrome, Streptococcus toxic shock syndrome, streptococcal TSS

1 clinical trial for this condition and its sub-types.

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Broader categories

Disease (680) Infectious disease (282) Toxic shock syndrome (206) Bacterial infectious disease (93) Syndromic disease (25) Streptococcal infection (18) Human disease (14) Gram-positive bacterial infections (6) Commensal bacterial infectious disease (0) Disease by body system or component (0)
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  • Can immune antibodies fight toxic shock in kids? small trial hopes to find out

    Disease control Completed

    This study tested whether giving intravenous immunoglobulin (IVIG) to children with toxic shock syndrome is practical and might help. Toxic shock is a rare but life-threatening reaction to bacterial toxins. The trial enrolled 30 children in intensive care, giving them either IVIG…

    Phase: PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Disease control

    Last updated Jun 26, 2026 14:21 UTC

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