Tic disorder
MONDO:0002420Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)
51 clinical trials for this condition and its sub-types.
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Broader categories
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Can a dopamine-blocking drug safely control tourette syndrome over years?
Disease control OngoingThis trial investigates the long-term safety of ecopipam, a drug that blocks dopamine D1 and D5 receptors, in children, adolescents, and adults with Tourette syndrome. Participants who completed a prior study may enroll and receive ecopipam for up to 24 weeks or longer. The main …
Phase: PHASE3 • Sponsor: Emalex Biosciences Inc. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New pill aims to quiet tourette tics in landmark trial
Symptom relief OngoingThis study tests an experimental drug called gemlapodect to see if it can safely reduce tics in people with Tourette syndrome. About 164 adults and teens with moderate to severe tics will take the drug or a placebo for 12 weeks. The main goal is to measure changes in tic severity…
Phase: PHASE2 • Sponsor: Noema Pharma AG • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Everyday therapists? study tests Non-Licensed CBT in hospitals
Symptom relief OngoingThis study looks at whether unlicensed professionals can successfully provide cognitive behavioral therapy (CBT) to patients in a general hospital. It includes 250 adults with conditions like anxiety, depression, OCD, and PTSD. The goal is to see if this approach improves psychol…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Brain scans reveal why tourette patients are hypersensitive to everyday stimuli
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand why many people with Tourette syndrome are overly sensitive to everyday sensations like touch or noise. Researchers will monitor brain activity, heart rate, and sweat responses in 50 adults with Tourette syndrome while they experience different sound…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC