Sensorineural hearing loss disorder

This early-stage trial tests a new cell therapy called Rincell-1 for adults with certain types of hearing loss who are getting a cochlear implant. The study will compare the safety and early effectiveness of receiving the cell therapy plus the implant versus the implant alone. Ab…

This trial tests whether two self-assessment methods in a smartphone app can generate hearing aid settings that match those from a standard hearing test. Adults with perceived mild-to-moderate hearing loss will use the app to self-test their hearing and also undergo conventional …

This study looks at whether a wearable insulin patch pump, guided by a continuous glucose monitor, can better control high blood sugar caused by high-dose steroids in people with sudden hearing loss and diabetes or prediabetes. About 44 participants will be randomly assigned to e…

This study tests whether injecting steroids directly into the inner ear can improve hearing in people with sudden, severe hearing loss that hasn't responded to standard treatment. Researchers will compare this method to standard steroid injections behind the eardrum. The trial in…

This study will test three new types of cochlear implants in 66 adults with severe hearing loss. The goal is to see if the implants improve speech understanding and overall hearing quality. Participants will receive the implant as part of their normal care, and researchers will t…

This early-stage trial tests whether tiny particles from stem cells can help treat severe sudden hearing loss. Nine adults will receive injections into the ear alongside standard care. The study checks for safety and whether hearing improves compared to a common steroid treatment…

This phase 3 trial tests whether adding aspirin and folic acid to standard treatment can improve recovery from sudden sensorineural hearing loss. The idea is that these drugs may improve blood flow to the inner ear. The study will enroll 142 adults with recent hearing loss and tr…

This pilot study tests a new imaging system that uses OCT and vibrometry to let doctors see the middle ear bones and measure how they move in response to sound. The study enrolls 500 adults with conductive or sensorineural hearing loss. The goal is to compare these detailed motio…

This study tests whether artificial intelligence (AI) can accurately help diagnose and triage patients with hearing loss and tinnitus, conditions affecting millions in the UK. Researchers will compare AI recommendations to those made by ear, nose, and throat doctors for 1,500 adu…

This study tests whether a program delivered by trained older adult peers can help people aged 60 and over with hearing loss. Participants receive an over-the-counter hearing device fitted to their needs along with communication training. The goal is to see if this affordable, co…

This trial tests whether a web-based, game-like training program can strengthen the connection between the ears and the brain in older adults with mild-to-moderate hearing loss. Over 12 weeks, participants complete listening and thinking exercises designed to improve speech under…

This trial tests whether a structured aural rehabilitation program, called CSSAR, can improve hearing aid outcomes for new adult users aged 55 and older with mild-to-moderate hearing loss. Participants will either receive standard audiological care or standard care plus the CSSAR…

This study tests a new hearing aid algorithm called SEDA-HA designed to help people with hearing loss understand speech better in noisy environments. Participants aged 16 and older with mild to severe bilateral sensorineural hearing loss will use a prototype hearing aid with the …

This study tests whether a cochlear implant placed just outside the inner ear, near the round window, can safely reduce severe tinnitus that has not responded to standard treatments. Six adults with long-term, high-impact tinnitus will receive the implant in a two-step procedure.…

This study tests a new wind noise canceller for hearing aids that aims to reduce bothersome wind sounds while keeping speech clear. About 25 adults with mild to moderate-severe hearing loss will compare the new canceller to an older version by listening to recordings and choosing…

This study compares two ways to insert a cochlear implant: using a robotic device or the standard manual method. Researchers want to see which approach leads to better hearing one year after surgery. The study will enroll 32 adults with hearing loss, randomly assigning them to on…

This study looks back at the medical records of 200 people who received a SONATA 2 cochlear implant. The goal is to understand how well the implant works over time in real-world settings, including speech recognition in quiet and noisy environments. Researchers will also analyze …

This study investigates whether auditory and cognitive training can help adults with cochlear implants understand speech better. Researchers will enroll 100 experienced implant users and randomly assign them to different training programs. The goal is to see if these intervention…

This study will follow 40 older adults (age 60+) with severe hearing loss who have or will receive a cochlear implant. Researchers want to see if the implant improves social interaction and thinking skills. Participants will fill out questionnaires, wear a small audio recorder fo…

This study aims to create a tool that predicts age-related hearing loss using artificial intelligence and blood samples. Researchers will analyze 15 years of data from 1,000 older adults and also test 100 seniors for proteins linked to memory problems. The goal is to identify ris…

This study will follow over 3,000 older adults for three years to see how age-related hearing loss is connected to dementia. Researchers will use hearing tests, cognitive assessments, and blood markers to build a 'Hearing Health Clock' and early screening tools. The goal is to be…

This pilot study will test whether over-the-counter (OTC) hearing aids are practical and acceptable for older adults with mild-to-moderate hearing loss who are at risk for dementia. Forty participants aged 50 and older will either use the hearing aids right away or wait three mon…

This study looks at 10 adults over 50 with hearing loss and one weak balance ear. It compares implanting the device in the weak-balance ear versus the good-balance ear. The goal is to see if choosing the weaker side helps reduce dizziness after surgery.

This study looks at whether objective measurements, like the stapedius reflex, can help doctors program cochlear implants more precisely. Currently, tuning relies on patients describing what they hear, which can be subjective. Researchers will test 60 adults with severe hearing l…