Perinatal disease

This trial compared two approaches for twin-to-twin transfusion syndrome (TTTS) stage 1: immediate laser surgery versus careful observation. 179 pregnant women with TTTS stage 1 and favorable conditions took part. The goal was to see which strategy leads to better survival and br…

This study looked at whether giving more red blood cell transfusions (liberal strategy) to extremely low birth weight babies (under 1000 grams) helps them survive without brain damage compared to a more restrictive approach. Over 1800 infants from NICUs were followed until 22-26 …

This study tested a simple, low-cost plastic ruler called the Bili-ruler to screen newborns for jaundice. Over 4,000 infants were checked with the ruler, a standard device, and visual inspection. The goal was to see if the ruler can accurately identify dangerous jaundice, especia…

This study tested whether a sensory mindfulness technique could help mothers of babies in the neonatal intensive care unit (NICU) produce more breast milk and feel better. 60 mothers who were pumping milk for their hospitalized infants took part. The approach involved mindfulness…

This study measured a substance called preptin in the umbilical cord blood of 72 newborns. Researchers compared levels in babies with low or high birth weight to those with normal weight, and also looked at babies born to mothers with diabetes. The goal was to see if preptin leve…

This completed study looked at 500 children aged 5 to 18 to understand how factors around birth, thinking abilities, and social-emotional skills are linked to learning difficulties and developmental disorders like ADHD or autism. Researchers compared children with and without the…

This study looked at 1,000 women who gave birth at age 45 or older to understand the risks and complications they face. Researchers examined issues like preterm birth, delivery complications, and how long mothers stayed in the hospital. The goal was to gather information to help …

This study looked at whether using a gentle breathing support (noninvasive ventilation) during the placement of a breathing tube in newborns can make the procedure safer and more successful. Researchers observed 50 infants who needed a breathing tube in the delivery room or inten…

This study looked at whether an Obstetric Comorbidity Index can predict severe health problems in women who had a C-section and experienced heavy bleeding. Researchers reviewed the records of 583 patients to see how well the index identified those at highest risk. The goal is to …