Ovarian dysfunction

This trial tests whether electro-thumbtack needle (ETN) therapy, a form of acupuncture with mild electrical stimulation, can improve the live birth rate in women with diminished ovarian reserve (DOR) undergoing in vitro fertilization (IVF). About 406 women with DOR will be random…

This study tests whether transplanting ovarian tissue from a sister can restore fertility and hormone production in women with premature ovarian failure (early menopause). Ten women will receive tissue from their non-identical sister, along with immunosuppressive drugs to prevent…

This study looks at whether making small punctures in the ovary during egg retrieval can help women with low ovarian reserve (DOR) produce more eggs in a later cycle. About 214 women undergoing IVF will be randomly assigned to get the puncture procedure or standard care. The main…

This study tests whether a single injection of goserelin, given just before a stem cell transplant, can help preserve ovarian function in women with blood cancers. The trial will enroll 64 women aged 14-50 and measure menstrual recovery six months after transplant. If successful,…

This study tests whether a single injection of goserelin, given just before a stem cell transplant, can help preserve ovarian function in women with severe aplastic anemia. The trial will enroll 132 women aged 14–50 and compare menstrual recovery rates six months after transplant…

This study tests whether a single injection of goserelin, given just before a stem cell transplant, can help preserve ovarian function in women with blood cancers. The trial will enroll 64 women aged 14 to 50 and measure if their menstrual cycles return naturally within six month…

This clinical trial tests whether a traditional Chinese herbal formula, Bushen Tongzhi, can improve pregnancy rates in women with diminished ovarian reserve who are undergoing IVF. About 348 women aged 22-39 will take either the herbal granules or a placebo three times daily for …

This Phase 3 trial will test whether adding a traditional Chinese herbal formula to the standard fertility drug letrozole can improve natural pregnancy rates in women aged 22–39 with diminished ovarian reserve (low egg supply). The study plans to enroll 320 women who will receive…

This study tests whether a 12-week program of diet changes, supplements, exercise, and better sleep can improve fertility scores in women aged 20-40 who show early signs of fertility decline. Researchers will enroll 384 women across six medical centers in China, using the OvaRePr…

This study tests whether ShouTai Pills, a traditional Chinese herbal remedy, can improve egg quality in women with diminished ovarian reserve (DOR) who are undergoing IVF. Researchers will analyze follicular fluid to identify biological markers that predict who might benefit. The…

This study looks at women with diminished ovarian reserve (DOR) — a condition where the ovaries have fewer eggs, making IVF harder. Researchers are examining specific RNA molecules in the fluid around eggs to see how they relate to egg quality and embryo development. The goal is …