Sister's ovary tissue may restore fertility in early menopause
NCT ID NCT06673004
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study tests whether transplanting ovarian tissue from a sister can restore fertility and hormone production in women with premature ovarian failure (early menopause). Ten women will receive tissue from their non-identical sister, along with immunosuppressive drugs to prevent rejection. The goal is to see if periods return and if pregnancy is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ovarian tissue transplant
- What this could lead to
- If successful, this could offer a way for women with premature ovarian failure to restore fertility and hormone function without needing an egg donor.
- What could go wrong
- This is a very small, early study with only 10 participants. The transplant requires lifelong immunosuppression, which carries risks like infection and organ damage. Success is not guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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