Oligospermia

This pilot study tests whether transplanting a man's own frozen testicular tissue, stored before childhood cancer treatment, can restore fertility. Twenty men with azoospermia (no sperm) who want children will undergo the procedure. Doctors will check if the graft produces sperm …

This study looks at whether drinking a daily serving of gazpacho, a cold tomato-based soup, can improve semen quality in men with low sperm counts or poor sperm movement. Eighty men will follow a Mediterranean diet for 12 weeks, with half also drinking gazpacho each day. Research…

This study tests whether taking probiotics daily for about 100 days can improve sperm count, movement, and shape in men with infertility. Sixty men aged 20 to 45 will be randomly assigned to receive either probiotics or a placebo. Researchers will measure sperm quality at the sta…

This early-stage study is testing a new drug called STSP-0902 to see if it is safe for men. It includes healthy volunteers and men with low sperm count or low sperm movement. The main goal is to check for side effects and how the drug moves through the body. This is a first step …

This study explores whether hyperbaric oxygen therapy (HBOT) can help men with low sperm count (oligospermia) improve their fertility. Researchers will measure changes in sperm count, shape, and movement in 15 participants. The goal is to see if HBOT offers a new, non-drug option…

This study investigates whether a specific mitochondrial DNA variant (MT-ND1 m.3700G>A) is associated with severe male infertility, specifically conditions where sperm production is absent or extremely low. Researchers analyzed existing medical records and biological samples from…

This observational study aims to identify and classify Traditional Medicine (TM) syndromes in men aged 18 to 60 with male infertility and oligoasthenoteratozoospermia (OAT) syndrome. Researchers will first review TM literature to list symptoms, then survey 300 participants and us…

This observational study aims to understand how the CFTR gene is regulated in epididymal cells, which may help explain male infertility linked to cystic fibrosis. Researchers will collect leftover tissue samples from 20 men already scheduled for surgery. No extra procedures are n…

This study aims to find genes that may cause infertility in people with non-obstructive azoospermia (low or no sperm) or primary ovarian insufficiency (early menopause). Researchers will collect saliva samples from 500 adults to look for genetic differences. No new treatments are…

This study tests a new lab technique called HyperSperm to see if it can make sperm move better and stay healthy. Researchers will collect semen samples from 300 men with different fertility issues and compare the new method to the standard one. The goal is to find a safer and mor…