Frozen testicle tissue may help cancer survivors become dads

NCT ID NCT07542626

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether transplanting a man's own frozen testicular tissue, stored before childhood cancer treatment, can restore fertility. Twenty men with azoospermia (no sperm) who want children will undergo the procedure. Doctors will check if the graft produces sperm and if that sperm can be used for in vitro fertilization.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

autologous transplantation of cryopreserved immature testicular tissue

What this could lead to

If successful, this could offer a way for men who became infertile after childhood cancer treatment to have biological children using their own frozen tissue.

What could go wrong

This is a very early pilot study with only 20 participants, so results may not apply widely. The graft may not produce viable sperm, and there is a risk of reintroducing cancer cells from the stored tissue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

azoospermia infertility disorder oligospermia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cliniques universitaires Saint-Luc, Université catholique de Louvain

    RECRUITING

    Brussels, 1200, Belgium

    Contact Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••