Frozen testicle tissue may help cancer survivors become dads

NCT ID NCT07542626

Recruiting now Disease control Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether transplanting a man's own frozen testicular tissue, stored before childhood cancer treatment, can restore fertility. Twenty men with azoospermia (no sperm) who want children will undergo the procedure. Doctors will check if the graft produces sperm and if that sperm can be used for in vitro fertilization.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: autologous transplantation of cryopreserved immature testicular tissue
What this could lead to: If successful, this could offer a way for men who became infertile after childhood cancer treatment to have biological children using their own frozen tissue.
What could go wrong: This is a very early pilot study with only 20 participants, so results may not apply widely. The graft may not produce viable sperm, and there is a risk of reintroducing cancer cells from the stored tissue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTOLOGOUS TRANSPLANTATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

azoospermia infertility disorder oligospermia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOLOGOUS TRANSPLANTATION AZOOSPERMIA OR SEVERE OLIGOZOOSPERMIA INFERTILITY

Contacts and locations

Locations

Cliniques universitaires Saint-Luc, Université catholique de Louvain
RECRUITING

Brussels, 1200, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.