Oligoasthenoteratozoospermia

This study tested whether letrozole (a drug that lowers estrogen) and L-carnitine (a natural supplement) could improve sperm quality in 90 men with unexplained infertility. Participants took one of the treatments or a combination for three months. The goal was to see changes in s…

This study tested whether adding platelet-rich plasma (PRP) from a man's own blood to his sperm sample could improve embryo development during IVF. Researchers compared embryos from 66 men with severe sperm disorders, half treated with PRP and half without. The goal was to see if…

This completed Phase 4 trial tested whether Guilu Erxian Oral Liquid, a traditional Chinese herbal remedy, can improve sperm count and movement in men with mild to moderate low sperm count or poor sperm motility. The study enrolled 360 married men aged 22 to 40 who also had a dia…

This study tested whether eating two ounces of walnuts each day could improve sperm count, movement, and shape in men with fertility issues. 80 men took part, comparing walnuts to a standard multivitamin. The goal was to see if a simple diet change could help with natural or assi…

This study looked at 200 men with sperm abnormalities to see if vacuoles (tiny holes) in the sperm head are linked to DNA damage. Researchers used high-powered microscopes and genetic tests to measure vacuole size and chromosome errors. The goal is to help doctors pick healthier …

This study looked at 248 men with very low or no sperm in their semen to see if a less-invasive, mini-incision surgery could successfully retrieve sperm. Researchers checked whether factors like hormone levels or medical history could predict who would benefit from this smaller p…

This study looked at 129 men with low or no sperm in their semen who had sperm surgically removed from the testicle (micro-TESE) for IVF. Researchers compared doing the sperm retrieval 24 hours versus 48 hours before the egg retrieval to see if timing affected live birth rates. T…