Ancient herbal tonic put to the test for male fertility
NCT ID NCT07270146
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 4 trial tested whether Guilu Erxian Oral Liquid, a traditional Chinese herbal remedy, can improve sperm count and movement in men with mild to moderate low sperm count or poor sperm motility. The study enrolled 360 married men aged 22 to 40 who also had a diagnosis of kidney essence deficiency. Participants received either the herbal liquid or a standard comparator, and researchers measured changes in total motile sperm count and other semen parameters.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Guilu Erxian Oral Liquid (a traditional Chinese herbal remedy)
- What this could lead to
- If it works, this could offer a treatment option for men with low sperm count or poor sperm movement related to kidney essence deficiency.
- What could go wrong
- This is a Phase 4 trial, but results are not yet published. The condition is subjective and the herbal remedy may not work better than existing treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Xi Yuan Hospital of China Academy of Chinese Medical Sciences
Beijing, China
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