Sperm vacuoles may reveal hidden DNA damage

NCT ID NCT02006446

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 200 men with sperm abnormalities to see if vacuoles (tiny holes) in the sperm head are linked to DNA damage. Researchers used high-powered microscopes and genetic tests to measure vacuole size and chromosome errors. The goal is to help doctors pick healthier sperm for fertility treatments.

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Conditions

The condition(s) this trial relates to.

aneuploidy male infertility oligoasthenoteratozoospermia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Laboratoire de Biologie de la Reproduction - CECOS - EA 4308, CHU - Hôpitaux de Rouen

    Rouen, 76031, France

  • Laboratoire de spermiologie, Hôpital Calmette, CHRU de Lille

    Lille, France