Nonsyndromic genetic hearing loss

This study tested a new cochlear implant (CI632) in 10 adults who have some low-frequency hearing but poor high-frequency hearing. The goal was to see if the implant improves speech understanding and overall hearing. Participants received the implant and were followed to measure …

This study tests whether infusing a child's own stored umbilical cord blood stem cells is safe for children with acquired sensorineural hearing loss. The trial enrolls children with moderate to profound hearing loss and aims to see if the infusion can improve inner ear function, …

This study tested a special hearing device called an auditory brainstem implant in 10 children aged 2 to 5 who are profoundly deaf due to missing or damaged inner ear parts. Unlike a cochlear implant, this device is placed directly on the brainstem during surgery. The main goal w…

This study tested a new device called CochSyn that measures brain waves to detect hearing damage. Researchers compared results from 65 adults with and without hearing difficulties. The goal was to see if the device can accurately identify different types of hearing loss and be ea…

This study looked at whether a computer algorithm could improve how a cochlear implant is set for people who have one implant and a hearing aid in the other ear. Nine adults with severe hearing loss took part. The goal was to see if the new settings helped them hear better in qui…

This study tested a daily dietary supplement called ACEMg (Soundbites) in 64 adults with hearing loss or tinnitus. Participants took the supplement for 24 weeks and completed hearing tests and symptom surveys at home using a smartphone app. The goal was to see if the supplement c…

This completed study tested whether adding gastrodin acupoint injections to standard care helps people with sudden hearing loss and vertigo. One hundred adults received either standard therapy alone or standard therapy plus injections into specific acupuncture points over four we…

This study tested a new virtual reality rehab program for adults with two cochlear implants who struggle to locate where sounds come from. Twelve participants completed 8 sessions over a month, using head movements and joystick feedback to practice sound localization. The goal wa…

This study looked at 324 people with hearing loss and an inner ear problem called enlarged vestibular aqueducts. Researchers collected DNA, hearing tests, and scans to find genes that may cause the condition. The goal was to learn more about why it happens, not to test a treatmen…

This study investigates whether a quick, painless electrical measurement called transimpedance matrix (TIM) can detect scar tissue (fibrosis) that sometimes forms inside the cochlea after cochlear implant surgery. Researchers will compare TIM results with CT scans in 180 adults w…

This study aims to find the genetic causes of hereditary hearing loss and balance disorders. Researchers will study families with these conditions, collecting medical history, blood or cheek swabs, hearing and balance tests, and sometimes scans. The goal is to identify genes and …

This study looked at whether hearing and vision loss are linked to delirium (sudden confusion) in older hospital patients. Over 1,500 participants answered screening questions and had their hearing and vision tested. In a smaller trial, researchers tested if posting communication…

This completed study enrolled 186 people with mild to moderate hearing loss to understand how damage to inner ear sensory cells and auditory neurons affects speech understanding, especially in noisy environments. Participants were fitted with hearing aids and tested on speech rec…

This completed study looked at 150 children with severe to profound hearing loss to find how many have a specific genetic form called DFNB9. Researchers collected medical and genetic data from routine care. The goal was to better understand this condition and pave the way for fut…

This study looked at how deaf people who were born deaf process reading in their brains. Researchers used brain scans to compare deaf and hearing readers. The goal was to understand how the brain adapts to reading without ever hearing speech sounds. 60 adults who are deaf and hav…

This study followed 50 children who received cochlear implants, measuring their brain's electrical responses to sounds and comparing them with speech and language test results over three years. The goal was to see if certain brain wave patterns could predict how well a child deve…