Nonsyndromic genetic hearing loss

This phase 3 trial tests whether an experimental drug called KP-100IT, injected into the spinal fluid, can help people with severe acute spinal cord injuries regain function. Participants, aged 18 to 89 with a complete loss of motor and sensory function (AIS grade A), receive fiv…

This early-stage trial tests a new cell therapy called Rincell-1 for adults with certain types of hearing loss who are getting a cochlear implant. The study will compare the safety and early effectiveness of receiving the cell therapy plus the implant versus the implant alone. Ab…

This trial tests whether two self-assessment methods in a smartphone app can generate hearing aid settings that match those from a standard hearing test. Adults with perceived mild-to-moderate hearing loss will use the app to self-test their hearing and also undergo conventional …

This pilot study tests a new imaging system that uses OCT and vibrometry to let doctors see the middle ear bones and measure how they move in response to sound. The study enrolls 500 adults with conductive or sensorineural hearing loss. The goal is to compare these detailed motio…

This study compares two ways to insert a cochlear implant: using a robotic device or the standard manual method. Researchers want to see which approach leads to better hearing one year after surgery. The study will enroll 32 adults with hearing loss, randomly assigning them to on…

This study tests a new care pathway for adults getting a cochlear implant. Instead of the usual nine clinic visits in the first year, the new plan uses early activation of the implant and remote monitoring visits. The goal is to see if this approach is at least as good for hearin…

This study looks back at the medical records of 200 people who received a SONATA 2 cochlear implant. The goal is to understand how well the implant works over time in real-world settings, including speech recognition in quiet and noisy environments. Researchers will also analyze …

This study looks at 10 adults over 50 with hearing loss and one weak balance ear. It compares implanting the device in the weak-balance ear versus the good-balance ear. The goal is to see if choosing the weaker side helps reduce dizziness after surgery.