Neurotic depression
MONDO:0024614A term used for any state of depression that is not psychotic.
Also known as: neurotic depression
47 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New therapy aims to help teens battling addiction and anxiety
Disease control CompletedThis study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to s…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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VA tests telemedicine blend to bring mental health care to rural veterans
Disease control CompletedThis study tested a blended collaborative care model that uses telemedicine to integrate mental health treatment into primary care at smaller VA clinics serving rural veterans. Researchers enrolled 318 veterans who screened positive for depression, alcohol use disorder, or PTSD. …
Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Could the sound of your voice reveal depression?
Diagnosis CompletedThis study tests a voice-analysis device designed to help clinicians screen for moderate to severe depression in adults. About 1,600 English-speaking adults aged 22 and older will record their voices, and the device's screening results will be compared with a standard clinical in…
Sponsor: Kintsugi Mindful Wellness, Inc. • Aim: Diagnosis
Last updated Aug 16, 2026 00:00 UTC
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Nurse Check-Ins after suicide attempt show promise in preventing repeat crisis
Prevention CompletedThis study tested whether personalized, intensive nursing follow-up (by phone, home visits, or hospital consultations) after a suicide attempt could prevent another attempt or crisis in people with mood disorders. 380 participants were followed for one year. The goal was to see i…
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Prevention
Last updated Jun 27, 2026 13:01 UTC
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Can online group therapy match In-Person for treating anxiety and depression?
Symptom relief CompletedThis study tests a therapy called the Unified Protocol, designed to help people with emotional disorders like anxiety and depression by improving emotional regulation. Researchers compare delivering the therapy in online group sessions versus in-person group sessions to see if bo…
Phase: NA • Sponsor: University of Coimbra • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Can dogs help teens with anxiety and depression? new study says maybe
Symptom relief CompletedThis study tested whether adding dog-assisted therapy to usual care helps teens aged 12-18 with mental health issues like anxiety, depression, and emotional dysregulation. 70 teens in a day hospital were randomly assigned to either get dog therapy plus usual care or usual care al…
Phase: NA • Sponsor: Hospital Clinic of Barcelona • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Online group therapy helps workers with depression get back on the job
Symptom relief CompletedThis study tested an online group program called Healthy Minds for people on sick leave due to depression, anxiety, or adjustment disorders. 123 participants either joined the 8-week program or received standard care. Researchers tracked their return to work, symptoms, and job fu…
Phase: NA • Sponsor: Université du Québec a Montréal • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Light therapy for depression: does season matter?
Symptom relief CompletedThis study looked at whether bright light therapy helps depression equally well in spring/summer compared to autumn/winter. Over 200 adults with depression received daily 30-minute light sessions for at least a week. Researchers measured symptom changes and followed up for three …
Sponsor: Geestelijke Gezondheidszorg Eindhoven (GGzE) • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Gym workouts boost recovery in young adults on antipsychotics
Symptom relief CompletedThis study tested whether a 4-month gym exercise program helps young adults (18-35) taking antipsychotic medication for psychosis or mood disorders feel better in their daily lives. 226 participants were randomly assigned to either continue their usual care or add gym workouts. R…
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Online mental health program shows promise for depression
Symptom relief CompletedThis study tested a digital mental health program for adults with depressive symptoms. The program includes nine online modules covering topics like positive thinking, relaxation, and healthy habits. Researchers compared results between people with diagnosed mood disorders and th…
Phase: NA • Sponsor: Chang Hsiu-Ju • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Art as medicine: study tests whether theatre, dance, and music ease depression
Symptom relief CompletedThis study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…
Phase: NA • Sponsor: KAVADIA ELENI • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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VR headsets could replace pills for anxiety and depression
Symptom relief CompletedThis study tested whether virtual reality (VR) sessions can help reduce anxiety and depression in people aged 12 to 25 who do not want to take medication. Forty participants completed five weekly VR sessions focused on relaxation, coping skills, and healthy habits. Researchers me…
Phase: NA • Sponsor: Istanbul Aydın University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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New psychotherapy shows promise for insomnia in mood disorders
Symptom relief CompletedThis study tested a new 8-session psychotherapy called ChronoS in 67 adults with mood disorders (bipolar or depression) and chronic insomnia. The therapy focuses on sleep-wake awareness and habits. Researchers measured changes in insomnia severity using a standard questionnaire. …
Phase: NA • Sponsor: Centre Hospitalier St Anne • Aim: Symptom relief
Last updated Jun 26, 2026 18:11 UTC
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Group therapy shows promise for teens battling anxiety and depression
Symptom relief CompletedThis study tested a group version of a therapy program called the Unified Protocol for teens with emotional disorders like anxiety and depression. Thirty-one adolescents took part in 16 weekly group sessions at a public mental health center in Spain, along with three parent sessi…
Phase: NA • Sponsor: Universidad Nacional de Educación a Distancia • Aim: Symptom relief
Last updated Jun 26, 2026 17:39 UTC
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Meditation rewires depressed Teens' brains, study finds
Knowledge-focused CompletedThis study looks at how a meditation program called TARA changes brain connections in teens aged 14 to 18 with mild or moderate depression. Researchers will use brain scans to see if meditation strengthens a key brain area and reduces depression symptoms. The goal is to understan…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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MRI reveals brain differences in violent suicide attempts
Knowledge-focused CompletedThis study used MRI brain scans and computer tasks to understand how people who attempted suicide make decisions. Researchers compared three groups: those who used violent means, those who used non-violent means, and healthy volunteers. The goal was to find brain activity pattern…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Job support program shows promise for mental health recovery
Knowledge-focused CompletedThis study tested a program called IPS-MA, which helps people with mood or anxiety disorders find and keep jobs or return to school. 326 adults who were unable to work within three months took part. The goal was to see if this support, added to their usual treatment, helped them …
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Therapist connection may boost sleep therapy success
Knowledge-focused CompletedThis study looked at 48 adults with mood disorders and insomnia to see if a strong relationship with their therapist helped them get better results from a new type of therapy called ChronoS. The therapy combines sleep scheduling, mindfulness, and stress management. Researchers me…
Phase: NA • Sponsor: Centre Hospitalier St Anne • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC