Myalgic encephalomeyelitis/chronic fatigue syndrome

This trial tests whether inebilizumab, an antibody that wipes out certain immune cells called B cells, can improve physical function in adults with ME/CFS that started after an infection. Participants receive three infusions over six months, and the study measures changes in mobi…

This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with mild to moderate chronic fatigue syndrome. 74 participants will receive either real treatment or a sham (placebo) for 60 sessions over 3 months. Researchers wi…

This study tests a treatment called Intermittent Hypoxia-Hyperoxia Treatment (IHHT) for people with ME/CFS or long COVID. The therapy uses a mask to deliver short cycles of low and high oxygen, aiming to improve energy and reduce inflammation. 104 patients will be randomly assign…

This study tests whether modafinil, a drug used for sleep disorders, can reduce severe fatigue in adults with inactive inflammatory bowel disease (IBD). Sixty participants will take either modafinil or a placebo for 8 weeks, starting at 100 mg daily with possible dose increases. …

This early study tests whether a low-level magnetic therapy device, used at home, is safe and practical for people with cognitive issues from brain injury, Long COVID, or Alzheimer's. About 30 adults will use the device regularly and complete computer-based thinking tests. The go…

This study tests whether a low dose of naltrexone can reduce fatigue in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Researchers will enroll 75 adults from Alabama and track their fatigue levels weekly through online surveys. The goal is to find the be…

This study tests a program called AIMSS-CARE for breast cancer patients who have joint and muscle pain from their hormone therapy. The program includes exercise, education, symptom tracking, and follow-up. Eighty-eight patients in Ethiopia will be randomly assigned to the program…

This study tests whether acupuncture can improve thinking and memory problems (brain fog) in people with chronic fatigue syndrome (ME/CFS) that started after COVID-19. About 99 adults will be randomly assigned to real acupuncture, fake acupuncture, or a waiting list for 8 weeks. …

This study tests whether a digital tool called MSCopilot Boost can reduce the impact of fatigue in people with multiple sclerosis better than standard care. The tool includes remote monitoring of walking, dexterity, vision, and cognition, plus a personalized telerehabilitation pr…