Could pressurized oxygen ease chronic fatigue? new trial aims to find out

NCT ID NCT07621068

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with mild to moderate chronic fatigue syndrome. 74 participants will receive either real treatment or a sham (placebo) for 60 sessions over 3 months. Researchers will measure physical performance, fatigue, and other symptoms to see if the therapy provides real relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)

What this could lead to

If it works, this could offer a new way to reduce fatigue and improve daily function for people with chronic fatigue syndrome.

What could go wrong

This is an early-stage trial with only 74 participants, and the sham control may reveal no benefit. The treatment is time-intensive (60 sessions) and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myalgic encephalomeyelitis/chronic fatigue syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)

    Zrifin, 70300, Israel