Could a nerve pain drug and exercise ease long COVID fatigue?
NCT ID NCT05967052
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the drug pregabalin, alone or with a rehabilitation program, can reduce chronic fatigue in people with post-COVID syndrome. Participants are adults aged 18 to 65 who had COVID-19 at least six months ago and still feel very tired. The trial compares four groups: pregabalin only, rehabilitation with a placebo, rehabilitation with pregabalin, or placebo only, over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pregabalin
What this could lead to
If it works, this could point toward a treatment for chronic fatigue after COVID-19, combining medication and rehabilitation.
What could go wrong
This is a small early-phase trial, so results may not apply to everyone. Pregabalin can cause side effects like dizziness and drowsiness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centrum Wsparcia Badań Klinicznych
Warsaw, Masovian Voivodeship, 02-637, Poland