Movement disorder
MONDO:0005395Neurological conditions resulting in abnormal voluntary or involuntary movement, which may impact the speed, fluency, quality and ease of movement.
Also known as: movement disease, movement disorder, movement disorders
805 clinical trials for this condition and its sub-types, 108 tagged with Movement disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Movement disorder
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Extrapyramidal and movement disease 0 trials · 149 incl. sub-types
1 sub-type
- Dystonic disorder 65 trials · 149 incl. sub-types Sub-types →
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Cerebellar ataxia 40 trials · 144 incl. sub-types
1 sub-type
- Hereditary cerebellar ataxia 0 trials · 116 incl. sub-types Sub-types →
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Multiple system atrophy 110 trials · 119 incl. sub-types
4 sub-types
- Pure autonomic failure 18 trials
- Multiple system atrophy, parkinsonian type 12 trials
- Multiple system atrophy, cerebellar type 3 trials
- Striatonigral degeneration 0 trials Sub-types →
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Essential tremor 102 trials · 104 incl. sub-types
6 sub-types
- Tremor, hereditary essential, 1 2 trials
- Tremor, hereditary essential, 2 0 trials
- Tremor, hereditary essential, 3 0 trials
- Tremor, hereditary essential, 4 0 trials
- Tremor, hereditary essential, 5 0 trials
- Tremor, hereditary essential, 6 0 trials
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Progressive supranuclear palsy 73 trials · 77 incl. sub-types
4 sub-types
- Supranuclear palsy, progressive, 1 5 trials
- Atypical progressive supranuclear palsy syndrome 1 trial · 4 incl. sub-types Sub-types →
- Supranuclear palsy, progressive, 2 0 trials
- Supranuclear palsy, progressive, 3 0 trials
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Huntington disease 76 trials
2 sub-types
- Juvenile Huntington disease 1 trial
- Westphal disease 0 trials
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Progressive non-fluent aphasia 23 trials · 44 incl. sub-types
1 sub-type
- Semantic dementia 32 trials Sub-types →
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Behavioral variant of frontotemporal dementia 21 trials · 42 incl. sub-types
3 sub-types
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Tourette syndrome 41 trials
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Corticobasal syndrome 19 trials
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Frontotemporal dementia with motor neuron disease 13 trials · 19 incl. sub-types
7 sub-types
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 5 trials
- Amyotrophic lateral sclerosis type 10 3 trials
- Amyotrophic lateral sclerosis type 6 1 trial
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 3 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 0 trials
- Frontotemporal dementia and/or amyotrophic lateral sclerosis 6 0 trials
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Chronic tic disorder 15 trials
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Choreatic disease 11 trials
5 sub-types
- Chorea gravidarum 0 trials
- Chorea, benign familial 0 trials
- Chorea, remitting, with nystagmus and cataract 0 trials
- Choreoathetosis, familial inverted 0 trials
- Hereditary progressive chorea without dementia 0 trials
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Neurodegeneration with brain iron accumulation 1 trial · 8 incl. sub-types
14 sub-types
- Neurodegeneration with brain iron accumulation 5 4 trials
- Pantothenate kinase-associated neurodegeneration 4 trials Sub-types →
- PLA2G6-associated neurodegeneration 1 trial Sub-types →
- Kufor-Rakeb syndrome 0 trials Sub-types →
- Woodhouse-Sakati syndrome 0 trials
- Aceruloplasminemia 0 trials
- Early-onset progressive encephalopathy-spastic ataxia-distal spinal muscular atrophy syndrome 0 trials
- Fatty acid hydroxylase-associated neurodegeneration 0 trials
- Neurodegeneration with brain iron accumulation 4 0 trials
- Neurodegeneration with brain iron accumulation 6 0 trials
- Neurodegeneration with brain iron accumulation 7 0 trials
- Neurodegeneration with brain iron accumulation 8 0 trials
- Neurodegeneration with brain iron accumulation 9 0 trials
- Neuroferritinopathy 0 trials
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Arthrogryposis 4 trials · 6 incl. sub-types
5 sub-types
- Freeman-Sheldon syndrome 1 trial Sub-types →
- Congenital contractural arachnodactyly 1 trial
- Boylan dew greco syndrome 0 trials
- Distal arthrogryposis Moore weaver type 0 trials
- Massa casaer ceulemans syndrome 0 trials
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Inherited Creutzfeldt-Jakob disease 5 trials
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Primary orthostatic tremor 5 trials
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Clonic hemifacial spasm 4 trials
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Familial congenital mirror movements 3 trials
4 sub-types
- Mirror movements 1 and/or agenesis of the corpus callosum 0 trials Sub-types →
- Mirror movements 2 0 trials
- Mirror movements 3 0 trials
- Mirror movements 4 0 trials
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Transient tic disorder 3 trials
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Opsoclonus-myoclonus syndrome 2 trials
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Lafora disease 1 trial
2 sub-types
- Myoclonic epilepsy of Lafora 1 0 trials
- Myoclonic epilepsy of Lafora 2 0 trials
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Unverricht-Lundborg syndrome 1 trial
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Benign shuddering attacks 1 trial
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Myoclonus, familial 1 trial
2 sub-types
- Myoclonus, familial, 1 0 trials
- Myoclonus, familial, 2 0 trials
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Psychogenic movement disorders 1 trial
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PRRT2-associated paroxysmal movement disorder 0 trials · 1 incl. sub-types
3 sub-types
- Episodic kinesigenic dyskinesia 1 1 trial
- Infantile convulsions and choreoathetosis 0 trials
- Seizures, benign familial infantile, 2 0 trials
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Intellectual disability-hyperkinetic movement-truncal ataxia syndrome 0 trials · 1 incl. sub-types
1 sub-type
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Huntington disease-like 3 0 trials
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2 sub-types
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Sandifer syndrome 0 trials
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Brain-lung-thyroid syndrome 0 trials
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1 sub-type
- Torsion dystonia 2 0 trials
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Epilepsy with myoclonic absences 0 trials
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Hereditary geniospasm 0 trials
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Hyperekplexia 0 trials
2 sub-types
- Hereditary hyperekplexia 0 trials Sub-types →
- Sporadic hyperekplexia 0 trials
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Isolated facial myokymia 0 trials
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Kuru 0 trials
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Lingual-facial-buccal dyskinesia 0 trials
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Neuroacanthocytosis 0 trials
2 sub-types
- VPS13A-related neurodegenerative disease 0 trials
- XK-related neurodegenerative disease 0 trials
Most studied deeper sub-types
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Virtual reality at home: a new hope for stroke recovery?
Disease control CompletedThis trial tests whether a home-based virtual reality rehabilitation program called Muvity can improve arm function, balance, and quality of life in people who had a stroke more than six months ago. Participants will be split into two groups: one doing the Muvity program at home …
Sponsor: Universitat Politècnica de Catalunya • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New Parkinson's drug shows promise in Year-Long trial
Disease control CompletedThis study tested the safety and effectiveness of tavapadon, an experimental drug, in 992 people with Parkinson's disease over 58 weeks. Participants took flexible doses of the medication to see how well it controlled symptoms and what side effects occurred. The goal was to under…
Phase 3 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New drug tavapadon tested to ease Parkinson's symptoms
Disease control CompletedThis Phase 3 trial tested whether tavapadon, a daily pill, can improve movement and daily activities in people with early Parkinson's disease. Over 300 participants took either tavapadon or a placebo for 27 weeks. The study measured changes in motor function and daily living skil…
Phase 3 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Can a drug calm uncontrollable movements? new trial tests tetrabenazine
Disease control CompletedThis Phase 3 trial tested whether tetrabenazine (Xenazine) can reduce involuntary movements in people with tardive dyskinesia, a condition caused by long-term use of antipsychotic medications. Fifty-four adults with persistent symptoms were randomly assigned to receive either tet…
Phase 3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Mind-Controlled hand therapy shows promise for spinal cord injury recovery
Disease control CompletedThis study tested whether a brain-computer interface (BCI) training program could improve hand and arm function in people with recent spinal cord injuries. Thirty participants used a system that reads brain signals during hand motor imagery exercises. The goal was to see if this …
Sponsor: I.R.C.C.S. Fondazione Santa Lucia • Aim: Disease control
Last updated Jun 26, 2026 16:58 UTC
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AI chatbot app aims to ease parental stress
Symptom relief CompletedResearchers are testing a smartphone app called Pai.ACT that uses acceptance and commitment therapy to help parents of children with special needs manage stress and improve well-being. The study enrolls 60 Cantonese-speaking parents in Hong Kong who care for children aged 2 to 8 …
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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A psychedelic compound may lift mood in Parkinson's, and a trial puts it to the test
Symptom relief CompletedResearchers are testing whether psilocybin, the active compound in magic mushrooms, can safely help people with Parkinson's disease who also struggle with depression or anxiety. In this pilot study, 12 participants receive two oral doses of psilocybin with psychological support. …
Phase 2 • Sponsor: Joshua Woolley, MD, PhD • Aim: Symptom relief
Last updated Sep 05, 2026 00:00 UTC
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Could a Self-Help guide transform parenting stress for families of kids with NDD?
Symptom relief CompletedThis trial tests a 12-week guided self-help program for parents of young children (ages 2-6) with neurodevelopmental disorders like autism or ADHD. The program combines a workbook, online modules, and group sessions to teach acceptance and mindfulness skills. The goal is to see i…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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New drug shows promise in taming tardive dyskinesia movements
Symptom relief CompletedThis study tested a drug called SD-809 (deutetrabenazine) in 298 people with moderate to severe tardive dyskinesia, a condition causing uncontrollable movements. Participants received either the drug or a placebo for 12 weeks. The main goal was to see if the drug reduced the seve…
Phase 3 • Sponsor: Auspex Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Beat the shakes: rhythmic sounds boost arm control in Parkinson's
Symptom relief CompletedThis study tested whether training with rhythmic sounds (like a beat) could help people with Parkinson's disease move their arms better. 38 participants did arm exercises with or without the sounds for 21 days. Those who used rhythmic sounds showed lasting improvements in hand de…
Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Could a headset at home ease Parkinson's symptoms?
Symptom relief CompletedThis study tested whether people with Parkinson's disease can safely use a brain stimulation device (tDCS) at home. Six participants aged 40 to 70 used the device for 20 minutes daily over a week, with video call support. The goal was to see if it's practical and safe, and to che…
Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Gentle moves may ease knee pain: new study shows promise
Symptom relief CompletedThis study tested a movement therapy called Mulligan mobilization in 36 people with knee osteoarthritis. The goal was to see if it could reduce pain and improve how muscles work. Participants were aged 50 to 70 with moderate knee pain. The therapy involves gentle, repeated moveme…
Sponsor: Istinye University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New drug targets stubborn tremors in Parkinson's
Symptom relief CompletedThis study tested a drug called suvecaltamide for people with Parkinson's disease who still have moderate to severe tremor despite taking other medications. Over 17 weeks, 169 participants received either the drug or a placebo, with doses adjusted for best effect. The goal was to…
Phase 2 • Sponsor: Jazz Pharmaceuticals • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Parkinson's patients try antioxidant supplements to boost brain health
Symptom relief CompletedThis study looked at whether nutritional supplements, specifically N-acetyl cysteine (NAC) given orally and intravenously, could support brain function in people with Parkinson's disease. The researchers measured dopamine activity and markers of inflammation in the brain using sp…
Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New wheelchair adapts to spasms, promises better comfort and safety
Symptom relief CompletedThis study tested a special wheelchair called NETTI that can switch between a dynamic mode (which moves with the user) and a static mode. Four people who have frequent involuntary muscle spasms that cause them to slide forward in their chair took part. Researchers measured how mu…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Brain study sheds light on Parkinson's and tics
Knowledge-focused CompletedThis completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Scientists scan brains to uncover chemical clues in dystonia
Knowledge-focused CompletedThis study used PET and MRI brain scans to measure how a brain chemical called acetylcholine works in people with dystonia, a condition that causes involuntary muscle twisting. Researchers compared 31 adults with cervical or DYT1 dystonia to healthy volunteers. The goal was to be…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Can a better butt workout fix your walk? new study investigates
Knowledge-focused CompletedThis study looks at whether adding movement retraining with feedback to a home exercise program for gluteal (buttock) muscles can improve movement quality in healthy young adults with coordination issues. 38 participants will be split into two groups: one doing gluteal exercises …
Sponsor: Louisiana State University Health Sciences Center Shreveport • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Walking analysis sheds light on rare genetic disorders
Knowledge-focused CompletedThis study looked at whether a special walking test (3D gait analysis) can help identify movement problems in people with rare genetic diseases like Tuberous Sclerosis and STXBP1. About 40 participants aged 6 and older who could walk without help took part. The goal was to see if…
Sponsor: Universiteit Antwerpen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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No more sticky markers? AI cameras could make gait analysis easier for kids
Knowledge-focused CompletedThis study tested whether a markerless motion capture system (using video cameras and AI) can replace the traditional method of placing sticky markers on children's skin to analyze their walking. Fifty children with walking difficulties walked over a walkway both with and without…
Sponsor: Alder Hey Children's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Robot lets hospital patients 'Visit' home virtually
Knowledge-focused CompletedThis study tested a telepresence robot called COVEALINK 2 that allows patients hospitalized for at least 2 months to remotely control a robot in their own home. Using a smartphone app, patients could move the robot around and talk with family and friends. The goal was to see how …
Sponsor: Association APPROCHE • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Can brain zaps restore hand function after stroke?
Knowledge-focused CompletedThis study tested two types of non-invasive brain stimulation (called paired associative stimulation) to see if they could help improve hand movement in people who had a stroke. 81 participants (60 stroke survivors and 24 healthy volunteers) took part. The main goal was to unders…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Can a special therapy program help preterm babies catch up on motor skills?
Knowledge-focused CompletedThis study looked at whether a physical therapy program based on the Bobath concept can help very preterm babies (born between 24 and 32 weeks) improve their motor skills and overall development after leaving the hospital. Sixty infants took part, with some receiving the therapy …
Sponsor: Universidad de Almeria • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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AI baby monitor: could algorithms spot motor delays?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can accurately identify movement problems in infants by analyzing videos of their motor skills. Researchers enrolled 122 full-term and preterm babies aged 2-4 months. The goal was to develop and validate AI algorithms that co…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Wrist-Worn gadget could help doctors monitor Parkinson's at home
Knowledge-focused CompletedThis study tested a wrist-worn device called the Personal KinetiGraph (PKG) to see if it can accurately measure movement problems in people with Parkinson's disease. Nineteen participants wore the device while researchers compared its readings to standard clinical tests and video…
Sponsor: Global Kinetics Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC