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New drug tavapadon tested to ease Parkinson's symptoms

NCT ID NCT04223193

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tested whether tavapadon, a daily pill, can improve movement and daily activities in people with early Parkinson's disease. Over 300 participants took either tavapadon or a placebo for 27 weeks. The study measured changes in motor function and daily living skills using a standard rating scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tavapadon
What this could lead to
If successful, tavapadon could offer a new treatment option to help control motor symptoms in early Parkinson's disease.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. Tavapadon may not prove significantly better than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain disorder central nervous system disorder movement disorder nervous system disorder neurodegenerative disease Parkinson disease parkinsonian disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

  • Albany, New York

    Albany, New York, 12208, United States

  • Barcelona

    Barcelona, Barcelona, 08035, Spain

  • Belgrade

    Belgrade, Belgrade, 11000, Serbia

  • Berlin

    Berlin, State of Berlin, 12163, Germany

  • Boca Raton, Florida

    Boca Raton, Florida, 33487, United States

  • Bochum

    Bochum, Bochum, 44791, Germany

  • Boston Neuro Research Center

    North Dartmouth, Massachusetts, 02747, United States

  • Budapest

    Budapest, Budapest, 1135, Hungary

  • Cassino

    Cassino, Cassino, 03043, Italy

  • Centrum Medyczne Hope Clinic Sebastian Szklener

    Lublin, 20-701, Poland

  • Centrum Medyczne NEUROMED

    Bydgoszcz, 85-163, Poland

  • Cincinnati, Ohio

    Cincinnati, Ohio, 45212, United States

  • Cleveland, Ohio

    Cleveland, Ohio, 44195, United States

  • Cracow

    Krakow, Cracow, 31-505, Poland

  • Cypress, Texas

    Cypress, Texas, 77429, United States

  • Dongdaemun-gu, Seoul

    Seoul, Dongdaemun-gu, 02447, South Korea

  • Fresno, California

    Fresno, California, 93710, United States

  • Gera

    Gera, Gera, 07551, Germany

  • Haeundae-gu, Busan

    Busan, Haeundae-gu, 48108, South Korea

  • Houston, Texas

    Houston, Texas, 77030, United States

  • Katowice

    Katowice, Katowice, 40-097, Poland

  • Khlong Luang, Pathum Thani

    Khlong Luang, Changwat Pathum Thani, 12120, Thailand

  • Kiev

    Kiev, Kyiv City, 04114, Ukraine

  • Kirkland, Washington

    Kirkland, Washington, 98034, United States

  • Lubbock, Texas

    Lubbock, Texas, 79410, United States

  • Lviv

    Lviv, Lviv Oblast, 79010, Ukraine

  • Macquarie Park, New South Wales

    Sydney, New South Wales, 2109, Australia

  • Maitland, Florida

    Maitland, Florida, 32751, United States

  • Marseille, France

    Marseille, France, 13385, France

  • Memphis, Tennessee

    Memphis, Tennessee, 38157, United States

  • Milano

    Milan, Milano, 20132, Italy

  • Muenchen

    München, Muenchen, 81377, Germany

  • Móstoles, Madrid

    Madrid, Madrid, 28938, Spain

  • Nai Muang, Ubon Ratchathani

    Nai Muang, Changwat Ubon Ratchathani, 34000, Thailand

  • Nantes CEDEX 1

    Nantes, Nantes, 44093, France

  • Ocala, Florida

    Ocala, Florida, 34470, United States

  • Pecs

    Pécs, Hungary, 7623, Hungary

  • Ratchathewi, Bangkok

    Ratchathewi, Bangkok, 10400, Thailand

  • Richmond, Virginia

    Richmond, Virginia, 23229, United States

  • Richmond, Virginia

    Richmond, Virginia, 23233, United States

  • Rome

    Rome, Rome, 00133, Italy

  • Round Rock, Texas

    Round Rock, Texas, 78681, United States

  • Rozzano Milano

    Rozzano, 20089, Italy

  • Siemianowice Slaskie

    Siemianowice Śląskie, Siemianowice Slaskie, 41-100, Poland

  • Songpa-gu, Seoul

    Seoul, Songpa-gu, 05505, South Korea

  • Syracuse, New York

    Syracuse, New York, 13210, United States

  • Tatabanya

    Tatabánya, 2800, Hungary

  • Torino

    Torino, 10126, Italy

  • Toulouse Cedex 9

    Toulouse, Toulouse, 31059, France

  • Vinnitsa

    Vinnitsa, Vinnitsa, 21050, Ukraine

  • Winter Park, Florida

    Winter Park, Florida, 32792, United States

  • Zhongzheng, Taipei

    Zhongzheng, Taipei, 100225, Taiwan

  • Zhongzheng, Taipei

    Zhongzheng, Taipei, 112062, Taiwan

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