Intracranial hypotension

This study tested whether measuring the optic nerve sheath with ultrasound can predict postdural puncture headache (PDPH) after spinal anesthesia. 176 adults having knee replacement surgery were scanned before and after the procedure. The goal was to see if changes in nerve sheat…

This study tested two drug combinations to prevent post-dural puncture headache (PDPH) in 50 surgical patients who had experienced PDPH before. One group received aminophylline plus acetaminophen, and the other received aminophylline plus dexamethasone. The goal was to see which …

This pilot study tested a simple procedure called a sphenopalatine ganglion block (SPGB) — applying numbing medicine (lidocaine) inside the nose — against standard care (bed rest and extra fluids) for people who developed a severe headache after an accidental spinal needle punctu…

This study tested two treatments for headaches that can happen after a spinal tap. One treatment uses a person's own blood (epidural blood patch), and the other uses a special substance made from their blood (plasma-rich fibrin). The goal was to see which works better to relieve …

This study tested whether an injection of plasma-rich fibrin (a substance made from the patient's own blood) could relieve severe headaches that sometimes occur after a spinal tap or epidural. Sixty adults with this type of headache received the injection through a special cathet…

This study looks at whether measuring the optic nerve sheath diameter—the lining around the nerve that connects the eye to the brain—using ultrasound can help doctors know if a treatment for spontaneous intracranial hypotension (a condition where low spinal fluid causes severe he…

This study looked at 98 women who had a blood patch to treat severe headaches caused by an accidental spinal fluid leak during labor. Researchers wanted to see if certain factors during the blood patch procedure were linked to headaches that last 1 to 6 months. The goal is to bet…

This study looked at 112 women who had spinal anesthesia for surgery to see how often they got post-dural puncture headaches and how severe they were. Researchers compared pregnant women (obstetric) to non-pregnant women (non-obstetric) to find out if pregnancy changes headache r…

This study looked at 40 adults who developed a headache after spinal anesthesia. Researchers used ultrasound to measure changes in the eye's optic nerve sheath, which can indicate brain pressure. They wanted to see if the size of the needle used for the anesthesia was related to …

This study looked at 90 adults with Marfan syndrome to compare spinal symptoms and daily limitations between those who have dural ectasia (a widening of the spinal sac) and those who do not. Researchers used questionnaires to measure pain, activity limits, and quality of life. Th…