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Intracranial hypotension
MONDO:0006811Reduction of cerebrospinal fluid pressure characterized clinically by headache which is maximal in an upright posture and occasionally by an abducens nerve palsy (see abducens nerve diseases), neck stiffness, hearing loss (see deafness); nausea; and other symptoms. This condition may be spontaneous or secondary to spinal puncture; neurosurgical procedures; dehydration; uremia; trauma (see also craniocerebral trauma); and other processes. Chronic hypotension may be associated with subdural hematomas (see hematoma, subdural) or hygromas. (From Semin Neurol 1996 Mar;16(1):5-10; Adams et al., Principles of Neurology, 6th ed, pp637-8)
31 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Withdrawn study on plasma patches for rare headaches leaves questions unanswered
Disease control TerminatedThis study planned to compare two methods of delivering a platelet-rich plasma patch to treat headaches caused by low spinal fluid pressure. The trial was withdrawn before any participants were enrolled, so no data was collected. The goal was to see if a simpler blind approach co…
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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AI boosts brain scan accuracy in massive new trial
Diagnosis ENROLLING_BY_INVITATIONThis study tests whether an AI tool can help radiologists read brain CT and MRI scans more accurately and quickly. Researchers will compare how well doctors, AI alone, and doctors using AI together can spot abnormalities, urgent findings, and classify diseases. The goal is to red…
Sponsor: Yaou Liu • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Leg workouts may stop spinal headaches after C-Section
Symptom relief OngoingThis study tests whether doing simple leg exercises after spinal anesthesia for a C-section can help reduce headaches and improve heart function. 120 women aged 18-40 will perform supervised isometric exercises during recovery. The goal is to find a safe, non-drug way to manage p…
Phase: NA • Sponsor: Karbala University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC